Which cephalosporin is often used to treat complicated skin and soft tissue infections?
- A. Cefazolin
- B. Cefepime
- C. Ceftaroline
- D. Cephalexin
Correct Answer: C
Rationale: Ceftaroline, a fifth-generation cephalosporin, is effective against complicated skin/soft tissue infections, including MRSA.
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How can the nurse find the most up-to-date information about emergency preparedness related to bioterrorism agents?
- A. Read textbooks devoted to the topic.
- B. Ask coworkers to explain current events.
- C. Read journal articles about bioterrorism agents.
- D. Visit the Centers for Disease Control and Prevention (CDC) Web site.
Correct Answer: D
Rationale: The most current information will be found on the CDC Web site because new information can be posted immediately whereas textbooks and journal articles take time to print. Coworkers may or may not remain current on emergency preparedness and should not be the primary source of information.
Drugs significantly affected by enzyme induction include the following except:
- A. Barbiturate
- B. Chlorpromazine
- C. Diphenyl hydantoin
- D. Warfarin
Correct Answer: B
Rationale: Barbiturates, phenytoin (diphenyl hydantoin), and warfarin are affected by enzyme induction; chlorpromazine is less so.
Release of the mineralcorticoids is stimulated with:
- A. Low concentration of \mathrm{Na}+ in the blood
- B. Hypokalemia
- C. Low concentration of angiotensin II in the blood
- D. Low concentration of \mathrm{Mg} 2+ in the blood
Correct Answer: A
Rationale: Low blood sodium stimulates aldosterone release via the renin-angiotensin system.
Following are the true receptors, except one
- A. Beta adrenergic receptors
- B. Na-K-ATP ase
- C. Phosphodiesterase
- D. Plasma proteins
Correct Answer: D
Rationale: Plasma proteins bind drugs but are not receptors.
A 57-year-old man was recently diagnosed with Type-2 diabetes mellitus and placed on a medication. He began having myalgias and feeling sick and later developed respiratory distress, so he went to the hospital. His pH was 7.2, and he had elevated blood lactate levels. Which drug is likely causing his problem?
- A. Acarbose
- B. Glyburide
- C. Metformin
- D. Pioglitazone
Correct Answer: C
Rationale: Metformin is associated with lactic acidosis, presenting with low pH and high lactate, especially in overdose or renal impairment.
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