Which cytochrome is responsible for drug metabolism?
- A. P-450
- B. C-3b
- C. C-3a
- D. C-2a
Correct Answer: A
Rationale: Cytochrome P-450 enzymes in the liver are primary for drug metabolism.
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A nurse is providing instructions to the parent of an adolescent client who has a new prescription for Albuterol, PO. Which of the following instructions should the nurse include?
- A. You can take this medication to abort an acute asthma attack.
- B. Tremors are an adverse effect of this medication.
- C. Prolonged use of this medication can cause hyperglycemia.
- D. This medication can slow skeletal growth rate.
Correct Answer: B
Rationale: Tremors are a common side effect of albuterol due to beta-agonist stimulation.
The nurse is preparing to administer a medication from a multidose bottle. The label is torn and soiled but the name of the medication is still readable. What is the nurses priority action?
- A. Discard the entire bottle and contents and obtain a new bottle.
- B. Find the drug information and create a new label for the bottle.
- C. Ask another nurse to verify the contents of the bottle.
- D. Administer the medication if the name of the drug can be clearly read.
Correct Answer: A
Rationale: When the drug label is soiled obscuring some information the safest action by the nurse is to discard the bottle and contents because drug labels contain a great deal of important information, far more than just the name of the drug. Concentration of the drug, expiration date, administration directions, and precautions may be missing from the label and so put the patient at risk. Looking up drug information in a drug handbook or consulting with another nurse will not supply the expiration date or concentration of medication. Be safe and discard the bottle and its contents.
Jim is being treated for hypertension. Because he has a history of heart attack, the drug chosen is atenolol. Beta blockers treat hypertension by:
- A. Increasing heart rate to improve cardiac output
- B. Reducing vascular smooth muscle tone
- C. Increasing aldosterone-mediated volume activity
- D. Reducing aqueous humor production
Correct Answer: B
Rationale: Beta blockers like atenolol reduce vascular tone and heart rate, lowering blood pressure.
A nurse is assessing a client who is taking Digoxin to treat heart failure. Which of the following findings is a manifestation of digoxin toxicity?
- A. Bruising
- B. Report of metallic taste
- C. Muscle pain
- D. Report of anorexia
Correct Answer: D
Rationale: Anorexia is a common early sign of digoxin toxicity.
Symptoms of folate deficiency include:
- A. Thinning of the hair
- B. Bruising easily
- C. Glossitis
- D. Numbness and tingling of the hands and feet
Correct Answer: C
Rationale: Glossitis (inflamed tongue) is a classic symptom of folate deficiency.