Nokea
Which drug undergoes extensive first-pass hepatic metabolism?
- A. Heparin
- B. Insulin
- C. Propranolol
- D. Nitroglycerin
Correct Answer: C
Rationale: Propranolol undergoes extensive first-pass metabolism in the liver. When administered orally, propranolol is extensively metabolized by the liver before reaching systemic circulation, leading to reduced bioavailability. This process is known as first-pass hepatic metabolism, which significantly affects the drug's effectiveness and necessitates higher oral doses compared to other routes of administration.
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A healthcare professional is reviewing the laboratory results of a client who is taking Warfarin for atrial fibrillation. Which of the following findings should the professional report to the provider immediately?
- A. INR of 4.0
- B. Potassium level of 4.5 mEq/L
- C. Creatinine level of 1.0 mg/dL
- D. BUN of 18 mg/dL
Correct Answer: A
Rationale: An INR of 4.0 indicates that the client's blood is clotting too slowly, increasing the risk of bleeding. This level is above the therapeutic range for a client on Warfarin therapy. Therefore, the healthcare professional should notify the provider immediately to prevent potential bleeding complications.
When teaching a client with a new prescription for Lithium, which instruction should the nurse include?
- A. Restrict fluid intake to 1,000 mL per day.
- B. Maintain a consistent sodium intake.
- C. Take the medication at bedtime.
- D. Expect to have frequent headaches.
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
A client has a new prescription for Levothyroxine to treat hypothyroidism. Which of the following instructions should be included in the teaching?
- A. Take this medication with food.
- B. Take this medication at bedtime.
- C. Expect to see results in 1 week.
- D. Do not discontinue the medication without consulting the provider.
Correct Answer: D
Rationale: The correct instruction for the client who has a new prescription for Levothyroxine to treat hypothyroidism is not to discontinue the medication without consulting the provider. Abrupt cessation could lead to the return of hypothyroid symptoms, emphasizing the importance of medical guidance when considering any changes to the treatment plan.
What is a common side effect of Albuterol?
- A. Paradoxical Bronchospasm
- B. Diarrhea
- C. Seizures
- D. Vision Loss
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
What is the antidote for Heparin?
- A. Protamine sulfate
- B. Narcan
- C. Romazicon
- D. Naloxone
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.