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Which immunoglobulin is specific to an allergic response?

  • A. IgA
  • B. IgE
  • C. IgB
  • D. IgG
Correct Answer: B

Rationale: The correct answer is B: IgE. IgE is specific to allergic responses as it binds to mast cells and basophils, triggering the release of histamine and other inflammatory mediators. IgA is more involved in mucosal immunity, IgG is involved in long-term immunity and opsonization, and IgM is the primary antibody in the primary immune response. IgB is not a known immunoglobulin. Therefore, IgE is the specific immunoglobulin associated with allergic responses due to its role in mediating hypersensitivity reactions.