Nokea
Which is the main mechanism of passing the infection with Listeria monocytogenes from man to man:
- A. alimentary mechanism
- B. transmission
- C. transplacental mechanism
- D. physical contact
Correct Answer: C
Rationale: The correct answer is C, transplacental mechanism. Listeria monocytogenes can cross the placenta, infecting the fetus during pregnancy. This mechanism allows the bacteria to be transmitted from mother to baby in utero. Alimentary mechanism (A) involves ingestion of contaminated food, not direct transfer between individuals. Transmission (B) is a broad term that doesn't specify the specific route of Listeria transmission. Physical contact (D) is not a common mode of Listeria transmission compared to transplacental transmission in the case of maternal-fetal infection.
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A patient was admitted to the hospital on the 7th day of the disease with complaints of high temperature, headache, pain in the muscles, especially in calf muscles. Dermal integuments and scleras are icteric. There is hemorrhagic rash on the skin. Urine is bloody. The patient was fishing two weeks ago. What is the most likely diagnosis?
- A. Leptospirosis
- B. Yersiniosis
- C. Salmonellosis
- D. Brucellosis
Correct Answer: A
Rationale: The most likely diagnosis is A: Leptospirosis. Leptospirosis is caused by the spirochete Leptospira interrogans and is commonly transmitted through contact with water contaminated by animal urine, such as in this case of fishing. The symptoms described match those of leptospirosis, including high fever, headache, muscle pain, jaundice, hemorrhagic rash, and bloody urine. The calf muscle pain is a characteristic symptom of leptospirosis known as "Weil's disease." Yersiniosis (B) typically presents with abdominal symptoms, Salmonellosis (C) with gastrointestinal symptoms, and Brucellosis (D) with flu-like symptoms. Therefore, based on the symptoms and history provided, Leptospirosis is the most likely diagnosis.
A patient presents with a history of diarrhea of several weeks duration. Which of the following may be the cause?
- A. Yersinia enterocolitica
- B. Bordetella pertussis
- C. Neisseria meningitidis
- D. Corynebacterium diphtheria
Correct Answer: A
Rationale: Rationale:
- Yersinia enterocolitica is a common cause of diarrhea due to contaminated food or water.
- It typically presents with symptoms such as abdominal pain, fever, and diarrhea.
- The other choices are unlikely causes of prolonged diarrhea, as Bordetella pertussis causes whooping cough, Neisseria meningitidis causes meningitis, and Corynebacterium diphtheria causes diphtheria.
The number of new cases of a disease over a certain period of time compared with the general healthy population is referred to as:
- A. incidence
- B. prevalence
- C. virulence
- D. mortality
Correct Answer: A
Rationale: The correct answer is A: incidence. Incidence refers to the number of new cases of a disease occurring within a specific time period in relation to the healthy population. It helps in understanding the risk of developing the disease. Prevalence (B) is the total number of existing cases at a given point in time. Virulence (C) is the severity of the disease once contracted. Mortality (D) refers to the number of deaths due to the disease, not the new cases. Therefore, the correct term for new cases is incidence.
During bacteriological examination of sputum of a child with choking cough and fever there were revealed glossy smooth colonies growing on casein-charcoal agar and reminding of mercury drops. Microscopic examination revealed short Gram-negative bacteria. What microorganism was secured from the sputum?
- A. Bordetella pertussis
- B. Haemophylus influenzae
- C. Corynebacterium dyphtheriae
- D. Klebsiella pneumoniae
Correct Answer: A
Rationale: The correct answer is A: Bordetella pertussis. Glossy smooth colonies growing on casein-charcoal agar resembling mercury drops indicate Bordetella pertussis, the causative agent of whooping cough. The presence of short Gram-negative bacteria further supports this identification. Option B, Haemophilus influenzae, typically grows as small, round, translucent colonies on chocolate agar. Option C, Corynebacterium diphtheriae, forms gray colonies on tellurite agar. Option D, Klebsiella pneumoniae, appears as mucoid colonies on MacConkey agar.
For shigella is true:
- A. They produce hydrogen sulfide
- B. They ferment lactose
- C. They are nonmotile
- D. All of them are mannitol positive
Correct Answer: C
Rationale: Step-by-step rationale:
1. Shigella is a nonmotile bacterium.
2. This lack of motility is a key characteristic used to differentiate it from other enteric bacteria.
3. Nonmotile nature of Shigella helps it to cause infections by invading the intestinal epithelial cells.
4. Therefore, choice C is correct as Shigella is indeed nonmotile.
Summary:
A: Incorrect - Shigella does not produce hydrogen sulfide.
B: Incorrect - Shigella does not ferment lactose.
D: Incorrect - Shigella is not mannitol positive.