Which is the most definitive diagnosis of leukemia?
- A. A detailed history that includes bone pain and recurrent infections
- B. A lumbar puncture to ascertain if leukemic cells are in the cerebral spinal fluid
- C. A CBC with differential to check the morphology of all the blood cells
- D. A bone marrow biopsy will show an infiltrate of blast cells
Correct Answer: D
Rationale: The correct answer is D: A bone marrow biopsy will show an infiltrate of blast cells. A bone marrow biopsy is the gold standard for diagnosing leukemia as it provides direct visualization of the bone marrow cells. In leukemia, there is an abnormal proliferation of immature cells called blast cells. Therefore, the presence of blast cells in the bone marrow biopsy confirms the diagnosis.
A: A detailed history may provide valuable information, but it is not definitive for diagnosing leukemia.
B: A lumbar puncture is more relevant for diagnosing central nervous system involvement in leukemia, not for confirming the diagnosis itself.
C: A CBC with differential can show abnormalities in blood cell counts, but it does not provide direct visualization of blast cells in the bone marrow.
E, F, G: No additional options provided.
In summary, the most definitive diagnosis of leukemia is confirmed through a bone marrow biopsy, which directly shows the presence of blast cells, distinguishing it from the other choices.
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A sign specific to red blood cell destruction (hemolytic) anemia is:
- A. Jaundice
- B. Pica
- C. Anorexia
- D. Tachycardia
Correct Answer: A
Rationale: Jaundice is the correct answer for red blood cell destruction anemia because it results from the breakdown of red blood cells, causing an increase in bilirubin levels. Jaundice presents as yellowing of the skin and eyes. Pica (eating non-food items), anorexia (loss of appetite), and tachycardia (rapid heart rate) are not specific signs of hemolytic anemia. Jaundice is a key indicator due to the excess bilirubin released from the destruction of red blood cells.
A 16-year-old with a chronic illness has recently become rebellious and is taking risks such as missing doses of his medication. What is the best explanation for this behavior?
- A. The child needs more discipline
- B. The child needs more socialization with peers
- C. The child is exhibiting normal adolescent behavior
- D. The child is demonstrating a need for more parental control
Correct Answer: C
Rationale: The correct answer is C. The child is exhibiting normal adolescent behavior. Adolescence is a period of identity formation, autonomy-seeking, and risk-taking. It is common for teenagers to rebel against authority figures, including parents and healthcare providers, as they strive for independence and self-discovery. This rebellious behavior, such as missing medication doses, can be a way for the teenager to assert control over their own life and make their own decisions. It is crucial for healthcare providers to recognize this normal developmental stage and approach the situation with understanding and support rather than punitive measures.
Other choices are incorrect because:
A: The child needing more discipline implies that the behavior is solely due to a lack of control or structure, which overlooks the developmental aspect of adolescence.
B: While socialization with peers is important, it may not address the underlying reasons for the rebellious behavior.
D: Imposing more parental control may exacerbate the rebellion and hinder the adolescent's autonomy development.
A child with a history of diabetes mellitus presents with sweating, confusion, and slurred speech. The nurse suspects the cause is:
- A. Hyperglycemia
- B. Hyperkalemia
- C. Hyponatremia
- D. Hypoglycemia
Correct Answer: D
Rationale: The correct answer is D: Hypoglycemia. In a child with a history of diabetes mellitus, sweating, confusion, and slurred speech indicate low blood sugar levels. Hypoglycemia can lead to neuroglycopenic symptoms like confusion and slurred speech. Hyperglycemia (choice A) would present with polyuria, polydipsia, and fruity breath. Hyperkalemia (choice B) can cause muscle weakness and cardiac arrhythmias. Hyponatremia (choice C) typically presents with weakness, fatigue, and confusion. In this case, the symptoms point towards hypoglycemia as the most likely cause.
Your patient has just returned from the OR following an arterial septal defect repair. You are reviewing your orders and question the fluid rate ordered. Your patient is 6 years old and weighs 50 pounds. Select the appropriate hourly maintenance fluid rate for your patient.
- A. 63 ml/hr
- B. 64 ml/hr
- C. 65 ml/hr
- D. 107 ml/hr
Correct Answer: A
Rationale: The appropriate hourly maintenance fluid rate for a 6-year-old patient weighing 50 pounds can be calculated using the Holliday-Segar method, which recommends 100 ml/kg/day for the first 10 kg of body weight, 50 ml/kg/day for the next 10 kg, and 20 ml/kg/day for each additional kg. Converting the patient's weight from pounds to kg (50 lbs / 2.2 = 22.73 kg), the calculation would be:
100 ml x 10 kg + 50 ml x 10 kg + 20 ml x 2.73 kg = 1000 ml + 500 ml + 54.6 ml = 1554.6 ml/day
To convert this to an hourly rate, divide by 24 hours: 1554.6 ml/day / 24 hours = 64.775 ml/hr, which rounds down to 63 ml/hr (Option A).
The other choices are incorrect because
Which are appropriate actions to manage a hospitalized child with hemophilia? (Select all that apply).
- A. Administer Factor VII for bleeding crises
- B. Administer platelets for bleeding crises
- C. Avoid unnecessary skin punctures
- D. Administer Ibuprofen for complaints of discomfort
Correct Answer: A,C
Rationale: The correct answers are A and C. Administering Factor VII helps in managing bleeding crises in hemophiliac patients. Factor VII aids in clotting, essential for stopping bleeding. Avoiding unnecessary skin punctures reduces the risk of bleeding episodes in hemophilia patients. Platelets (B) and Ibuprofen (D) are not appropriate for managing hemophilia. Platelets do not address the underlying clotting factor deficiency in hemophilia, and Ibuprofen can worsen bleeding due to its antiplatelet effects.