Nokea
Which is the most prominent immunoglobulin class present in external secretions
- A. IgG
- B. IgM
- C. IgA
- D. IgE
Correct Answer: C
Rationale: The correct answer is C: IgA. IgA is the most prominent immunoglobulin class present in external secretions like saliva, tears, and mucus. It plays a crucial role in mucosal immunity by preventing pathogens from entering the body. IgG is mainly found in the blood and tissues, IgM is the first antibody produced in response to an infection, and IgE is involved in allergic reactions. IgA's presence in external secretions helps protect the body from infections at mucosal surfaces, making it the correct choice in this context.
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A patient who has been taking tetracycline for a long time has developed candidosis of mucous membranes. What drug shoul administered for its treatment?
- A. Itraconazole
- B. Griseofulvin
- C. Nitrofungin
- D. Amphotericin
Correct Answer: A
Rationale: The correct answer is A: Itraconazole. Itraconazole is an antifungal medication commonly used to treat candidosis. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This action disrupts the integrity of the fungal cell membrane, leading to cell death. Griseofulvin (B) is primarily used to treat fungal infections of the skin and nails, not mucous membranes. Nitrofungin (C) is not commonly used for candidosis treatment. Amphotericin (D) is a potent antifungal medication but is typically reserved for severe or systemic fungal infections due to its potential side effects.
Streptococci are:
- A. Gram-positive, short rod shaped bacteria and size 4-6 µm
- B. Gram-negative, rounded or lanceolate shape and size 0,5-1 µm
- C. Gram-negative, short rod shaped bacteria and size 4-6 µm
- D. Gram-positive, spherical or lanceolate shape and size 0,5-1 µm
Correct Answer: D
Rationale: The correct answer is D because Streptococci are Gram-positive bacteria, typically spherical in shape, and range from 0.5-1 µm in size.
A is incorrect as streptococci are not rod-shaped and are usually smaller in size. B is incorrect as they are not Gram-negative and are not typically of such small size.
C is incorrect as streptococci are not Gram-negative and are not usually rod-shaped. Thus, based on their characteristics, the correct answer is D.
Which of the following statements is FALSE regarding B cells?
- A. B cells that recognize high concentrations of antigen (self) in the absence of other signals undergo apoptosis in the bone marrow
- B. Bone marrow stem cells migrate to the thymus and develop into B cells
- C. B cells synthesize antibodies and put them on their cell surface
- D. B cells can undergo class switching and produce a different antibody type
Correct Answer: B
Rationale: B cells develop in the bone marrow, not the thymus. Firstly, hematopoietic stem cells in the bone marrow give rise to B cells. They undergo maturation and selection processes in the bone marrow, not in the thymus. Therefore, choice B is false. On the other hand, choices A, C, and D are correct. A is true because B cells with high affinity to self-antigens undergo apoptosis to prevent autoimmunity. C is true since B cells synthesize antibodies which can be displayed on their surface as B cell receptors. D is true because B cells can undergo class switching to produce different types of antibodies based on the immune response requirements.
Acne is caused by:
- A. Staphylococcus aureus
- B. Staphylococcus epidermidis
- C. Streptococcus pyogenes
- D. Propionibacterium acnes
Correct Answer: D
Rationale: The correct answer is D: Propionibacterium acnes. This bacterium plays a key role in acne formation by colonizing hair follicles, leading to inflammation and acne lesions. It produces fatty acids that contribute to the development of acne. Staphylococcus aureus (A) and Staphylococcus epidermidis (B) are not directly linked to acne. Streptococcus pyogenes (C) is associated with skin infections but not acne. In summary, Propionibacterium acnes is the primary bacterium responsible for acne due to its ability to induce inflammation and follicular blockages.
Which bacteria are commonly associated with food poisoning?
- A. Clostridium botulinum and Staphylococcus aureus
- B. Bacillus anthracis and Mycobacterium tuberculosis
- C. Treponema pallidum and Neisseria gonorrhoeae
- D. Escherichia coli and Klebsiella pneumoniae
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum and Staphylococcus aureus. Clostridium botulinum produces a potent neurotoxin causing botulism, commonly associated with improperly canned foods. Staphylococcus aureus produces toxins causing symptoms of food poisoning. Bacillus anthracis and Mycobacterium tuberculosis are not typically associated with food poisoning. Treponema pallidum and Neisseria gonorrhoeae are bacteria causing sexually transmitted infections. Escherichia coli and Klebsiella pneumoniae are not directly linked to food poisoning.