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Which may be given to high-risk children after exposure to chickenpox to prevent varicella?

  • A. Acyclovir (Zovirax)
  • B. Varicella globulin
  • C. Diphenhydramine hydrochloride (Benadryl)
  • D. VCZ immune globulin (VariZIG)
Correct Answer: D

Rationale: VCZ immune globulin (VariZIG) is given to high-risk children after exposure to chickenpox to prevent varicella. VariZIG contains antibodies against the varicella-zoster virus, providing passive immunity to the child. This can help reduce the severity of the infection or prevent it altogether in high-risk individuals. Acyclovir (Zovirax) is an antiviral medication used to treat varicella infections but is not typically used for prevention post-exposure. Varicella globulin is not a treatment for varicella. Diphenhydramine hydrochloride (Benadryl) is an antihistamine and is not used for preventing varicella post-exposure.