Nokea
Which of the following adverse effects of chronic high-dose prednisone administration represents a mineralocorticoid effect?
- A. Buffalo hump
- B. Easy bruising
- C. Edema
- D. Moon facies
Correct Answer: C
Rationale: Edema is a mineralocorticoid effect of prednisone due to sodium and water retention.
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Which phenothiazine has the least extra pyramidal effect
- A. Thioridazine
- B. Chlorpromazine
- C. Triflupromazine
- D. Fluphenazine
Correct Answer: A
Rationale: Thioridazine has fewer extrapyramidal effects.
The nurse would expect to see an adjusted dosage in what patients? (Select one that does not apply.)
- A. Young adult women
- B. older adults
- C. Infants
- D. Neonates
Correct Answer: A
Rationale: Infants, neonates, and older adults require dosage adjustments due to differences in metabolism and organ function.
Pentobarbitone is
- A. Long acting barbiturates
- B. Short acting barbiturates
- C. Ultra short acting barbiturates
- D. Intermediate acting barbiturates
Correct Answer: D
Rationale: Pentobarbitone (pentobarbital) is classified as an intermediate-acting barbiturate, with a duration of action between short-acting and long-acting barbiturates.
Serum digoxin levels are monitored for potential toxicity. Monitoring should occur:
- A. Within 6 hours of the last dose
- B. Because a reference point is needed in adjusting a dose
- C. After three half-lives from the starting of the drug
- D. When a patient has stable renal function
Correct Answer: C
Rationale: Monitoring after three half-lives (steady state) ensures accurate therapeutic levels.
John has clonidine, a centrally acting adrenergic blocker, prescribed for his hypertension. He should:
- A. Not miss a dose or stop taking the drug because of potential rebound hypertension
- B. Increase fiber in the diet to treat any diarrhea that may occur
- C. Reduce fluid intake to less than 2 liters per day to prevent fluid retention
- D. Avoid sitting for long periods, as this can lead to deep vein thrombosis
Correct Answer: A
Rationale: Clonidine withdrawal can cause rebound hypertension, making adherence critical.