Nokea
Which of the following anti inflammatory drugs is ineffective in gout?
- A. Piroxicam
- B. Tolmetin
- C. Aspirin
- D. Celecoxib
Correct Answer: C
Rationale: Aspirin increases uric acid levels, worsening gout.
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A nurse is monitoring a client who takes aspirin 81 mg PO daily. The nurse should identify which of the following manifestations as adverse effects of daily aspirin therapy? (Select one that does not apply.)
- A. Hypertension
- B. Coffee-ground emesis
- C. Tinnitus
- D. Nausea
Correct Answer: A
Rationale: Aspirin can cause GI bleeding , tinnitus , and nausea ; 'possessias' is likely a typo.
A 15 year old girl experiences epileptic fits during her menstrual periods. Which ONE of the following drugs is best suited for the management of her condition?
- A. Ethosuximide
- B. Valproic acid
- C. Phenytoin
- D. Corticosteroids
Correct Answer: B
Rationale: Valproic acid is effective for catamenial epilepsy and tonic-clonic seizures.
Which of the following medications has not hypoglycemic effect:
- A. Insulin
- B. Glucagon
- C. Metformin
- D. Glibenclamid
Correct Answer: B
Rationale: Glucagon raises blood glucose levels, unlike the others which lower it.
You are the home health nurse caring for a 77-year-old patient with congestive heart failure. When assessing this patient, in relation to their drug therapy, what is one thing that would be important for you to include in your assessment?
- A. Patient's age
- B. Required lifestyle changes
- C. Family members in the community
- D. Compliance with nutritional recommendations
Correct Answer: B
Rationale: Lifestyle changes (e.g., salt restriction) impact CHF drug therapy efficacy and adherence, critical for assessment.
A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is inactivated by the body may lead to:
- A. Decreased effectiveness of irinotecan in the treatment of cancer
- B. Increased adverse drug reactions, such as neutropenia
- C. Delayed metabolism of the prodrug irinotecan into the active metabolite SN-38
- D. Increased concerns for irinotecan being carcinogenic
Correct Answer: B
Rationale: UGT1A1 mutations slow SN-38 inactivation, raising neutropenia risk , not affecting efficacy or activation .