Which of the following chromosomal abnormalities of childhood ALL carries the highest risk of relapse despite intensive chemotherapy?
- A. t(9;22)
- B. t(4;11)
- C. hypodiploidy
- D. t(1;19)
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
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During the routine exam of an infant the parents state a 5th degree family history of adenomatous polyposis. The statement that should be included during the discussion is the infant is at increased risk of colonic adenocarcinoma
- A. the infant is at increased risk of acute lymphocytic leukemia
- B. the infant is at increased risk of intestinal Burkitt lymphoma
- C. the infant is at increased risk of hepatoblastoma
- D. the infant is at increased risk of germ cell tumor
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
A healthcare professional is assessing a child who has nephrotic syndrome. Which of the following findings should the healthcare professional expect?
- A. Hypotension
- B. Hyperglycemia
- C. Facial edema
- D. Weight gain
Correct Answer: D
Rationale: In nephrotic syndrome, there is increased permeability of the glomerular filtration barrier, leading to protein loss in the urine. This results in hypoalbuminemia, causing fluid retention and edema. Therefore, weight gain due to fluid retention is a common finding in children with nephrotic syndrome.
The healthcare provider is providing care to a child who was treated with aspirin during a viral infection. Which clinical manifestations should cause the healthcare provider concern?
- A. Nausea, vomiting, and confusion
- B. Headache, vomiting, and seizures
- C. Sore throat, moist respirations, and cough
- D. Fever, rash, and photophobia
Correct Answer: A
Rationale: The symptoms of nausea, vomiting, and confusion are concerning as they are indicative of Reye's syndrome, a rare but serious condition associated with aspirin use in children during viral illnesses. Reye's syndrome can lead to severe complications, including brain and liver damage, hence prompt recognition and management are crucial.
The healthcare provider is assessing an infant brought to the clinic due to diarrhea. The infant is alert but has dry mucous membranes. Which additional assessment data indicates to the healthcare provider that the infant is experiencing an early to moderate stage of dehydration?
- A. Bradycardia
- B. Tachycardia
- C. Increased blood pressure
- D. Normal fontanels
Correct Answer: B
Rationale: Tachycardia is a common early sign of dehydration in infants, especially when presenting with dry mucous membranes and diarrhea. The increased heart rate is the body's compensatory mechanism to maintain cardiac output in response to dehydration. Bradycardia, increased blood pressure, and normal fontanels are not typically associated with early to moderate dehydration in infants.
The age by which the child can make a tower of 9 cubes and imitates a circular stroke is
- A. 24 mo
- B. 30 mo
- C. 36 mo
- D. 42 mo
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.