Which of the following conditions results primarily from mutation in the gene encoding Vitamin D receptor?
- A. Vitamin D dependent rickets type 1
- B. Vitamin D dependent rickets type 2
- C. X-linked hypophosphatemic rickets
- D. Autosomal dominant hypophosphatemic rickets
Correct Answer: B
Rationale: Vitamin D dependent rickets type 2 is caused by mutations in the vitamin D receptor gene, leading to resistance to vitamin D.
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An overweight, young adult made who was recently diagnosed with type 2 diabetes mellitus is admitted for a hernia repair. He tells the nurse that he is feeling very weak and jittery. Which actions should the nurse implement? (Select all that apply.)
- A. Check his fingerstick glucose level
- B. Assess his skin temperature and moisture
- C. Measure his pulse and blood pressure
- D. Document anxiety on the surgical checklist
Correct Answer: C
Rationale: These actions help assess for hypoglycemia, a common issue in diabetic patients, and ensure appropriate intervention.
Despite the use of antibiotic agents, mortality remains high, in the range of 20-25%. Serious morbidity occurs in 50-60% of children with documented infective endocarditis. Of the following, the MOST common morbidity is
- A. heart failure
- B. pulmonary emboli
- C. mycotic aneurysms
- D. acquired ventricular septal defect
Correct Answer: A
Rationale: Heart failure is the most common morbidity in children with infective endocarditis.
Proximal renal tubular functions include:
- A. HCO3 secretion
- B. Sodium reabsorption
- C. Ammonia production
- D. Urine concentration
Correct Answer: B
Rationale: Sodium reabsorption
Membranous glomerulonephritis:
- A. Is typically associated with immune complex deposition
- B. Presents with nephritic syndrome
- C. Is associated with highly selective proteinuria
- D. Deposits of IgG on the glomerular membrane
Correct Answer: A
Rationale: Membranous glomerulonephritis is characterized by immune complex deposition, particularly IgG, on the glomerular basement membrane, leading to proteinuria.
Left axis deviation of the QRS complex is associated with all the following except
- A. Inflow ventricular septal defect
- B. Pulmonary atresia with intact interventricular septum
- C. Double outlet right ventricle with subaortic ventricular septal defect
- D. Noonan syndrome with pulmonary stenosis
Correct Answer: A
Rationale: Left axis deviation is not typically associated with inflow ventricular septal defect.