Nokea
Which of the following drugs do not cross the placenta
- A. Dilantin
- B. Diazepam
- C. Acinocoumarin
- D. Heparin
Correct Answer: D
Rationale: Heparin does not cross the placenta due to its large size.
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Which of the following can be used for treatment of hypothyroidism:
- A. Liothironine
- B. Iodides (lugol solution)
- C. Carbimazole
- D. Methimazole
Correct Answer: A
Rationale: Liothyronine (T3) is used to replace thyroid hormone in hypothyroidism.
Which statement is correct regarding glucagon:
- A. Causes hypoglicemia
- B. Causes hyperglicemia
- C. Haven't affect blood glucose level in blood
Correct Answer: B
Rationale: Glucagon causes hyperglycemia by stimulating glycogenolysis and gluconeogenesis in the liver.
Clinical dosing of Bethanechol:
- A. Begins at the highest effective dose to obtain a rapid response
- B. Starts at 5 mg to 10 mg PO and is repeated every hour until a satisfactory clinical response is achieved
- C. Requires dosing only once daily
- D. Is the same for both the oral and parenteral route
Correct Answer: B
Rationale: Bethanechol is titrated hourly from 5-10 mg to achieve the desired effect.
Which of the following is a disadvantage of using oral drugs
- A. First pass effect
- B. Low bioavailability
- C. Overdose overcome by antidotes
- D. A and B
Correct Answer: D
Rationale: Oral drugs face the first-pass effect and often have lower bioavailability due to liver metabolism, making D (A and B) the correct combined disadvantage.
The following are recognized effects of propranolol except
- A. Increases microcoronary blood flow
- B. Decrease in heart rate
- C. Decrease in cardiac output
- D. Reduction in ventricular systolic pressure
Correct Answer: A
Rationale: Propranolol reduces coronary flow; other effects are correct.