Which of the following drugs used for gout decreases net renal tubular reabsorption of uric acid?
- A. Hypoxanthine
- B. Indomethacin
- C. Colchicine
- D. Allopurinol
Correct Answer: C
Rationale: Colchicine reduces inflammation but also decreases uric acid reabsorption indirectly.
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A nurse in a provider's office is reviewing the medical record of a client who is pregnant and is at her first prenatal visit. Which of the following immunizations may the nurse administer safely to this client?
- A. Varicella vaccine
- B. Rubella vaccine
- C. Inactivated influenza vaccine
- D. Measles vaccine
Correct Answer: C
Rationale: Inactivated influenza vaccine is safe in pregnancy; live vaccines (A, B, D) are contraindicated.
Under new U.S. Food and Drug Administration labeling, Pregnancy Categories will be:
- A. Strengthened with a new coding such as C+ or C- to discern when a drug is more or less toxic to the fetus
- B. Changed to incorporate a pregnancy risk summary and clinical considerations on the drug label
- C. Eliminated, and replaced with a link to the National Library of Medicine TOXNET Web site for in-depth information regarding pregnancy concerns
- D. Clarified to include information such as safe dosages in each trimester of pregnancy
Correct Answer: B
Rationale: FDA replaced categories with risk summaries and clinical considerations for clearer, narrative-based guidance, effective 2015.
Which name identifies a drug listed by the US Food and Drug Administration (FDA)?
- A. Brand
- B. Nonproprietary
- C. Official
- D. Trademark
Correct Answer: C
Rationale: The official name is the name under which a drug is listed by the FDA. The brand name, or trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic, name is provided by the United States Adopted Names Council.
There is evidence that dietary supplementation or adequate intake of fish oils and omega-3 fatty acids have well-documented:
- A. Concern for developing cardiac dysrhythmias
- B. Anti-inflammatory effects
- C. Total cholesterol-lowering effects
- D. Effects on fasting blood sugar
Correct Answer: B
Rationale: Omega-3 fatty acids have proven anti-inflammatory effects, beneficial in cardiovascular health.
Art is a 55-year-old smoker who has been diagnosed with angina and placed on nitrates. He complains of headaches after using his nitrate. An appropriate reply might be:
- A. This is a parasympathetic response to the vasodilating effects of the drug.
- B. Headaches are common side effects with these drugs. How severe are they?
- C. This is associated with your smoking. Let's work on having you stop smoking.
- D. This is not related to your medication. Are you under a lot of stress?
Correct Answer: B
Rationale: Headaches are a common nitrate side effect due to vasodilation.