Nokea
Which of the following has a strong anti-inflammatory effect:
- A. Prednisolone
- B. Triamcinolone
- C. Dexamethasone
- D. Prednisone
Correct Answer: C
Rationale: Dexamethasone has a strong anti-inflammatory effect due to its high glucocorticoid potency.
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In the presence of picrotoxin, diazepam is less efficacious at causing sedation, regardless of the dose. Picrotoxin by it self has no sedative effect even at the highest dose. Which of the following is correct?
- A. Picrotoxin is not a competitive antagonist
- B. Diazepam is a full agonist, and picrotoxin is a partial agonist
- C. Diazepam is less efficacious than is picrotoxin
- D. Diazepam is less potent than is picrotoxin
Correct Answer: A
Rationale: Picrotoxin reduces diazepam's maximal effect (efficacy), not potency, indicating noncompetitive antagonism.
Pick the true statement:
- A. Amox- Clavulanic, Clavulanic increases amox activity
- B. Sublactum is used in treatment of Leprosy
- C. Aztreonam is a metabolite of clarithromycin
- D. Cilastatin imipenam- cilastatin prevents hydrolysis of imipenam
Correct Answer: B
Rationale: Sulbactam is used in leprosy treatment; other statements are incorrect (e.g., clavulanic enhances amoxicillin, cilastatin protects imipenem).
A nurse is caring for a school-age child who has a new prescription for Atomoxetine. The nurse should monitor the client for which of the following adverse effects of this medication?
- A. Kidney toxicity
- B. Liver damage
- C. Seizure activity
- D. Adrenal insufficiency
Correct Answer: B
Rationale: Atomoxetine can cause liver damage , a rare but serious effect to monitor.
Henry is 82 years old and takes two aspirin every morning to treat the arthritis pain in his back. He states the aspirin helps him to 'get going' each day. Lately he has had some heartburn from the aspirin. After ruling out an acute GI bleed, what would be an appropriate course of treatment for Henry?
- A. Add an H2 blocker such as ranitidine to his therapy
- B. Discontinue the aspirin and switch him to Vicodin for the pain
- C. Decrease the aspirin dose to one tablet daily
- D. Have Henry take an antacid 15 minutes before taking the aspirin each day
Correct Answer: A
Rationale: An H2 blocker reduces aspirin-induced heartburn; stopping or antacids don't address chronic use.
When taking a medication history on a patient why should the nurse ask about the use of complementary or alternative therapies?
- A. Patients starting on new drugs are usually not compliant with medical regimens.
- B. Many drug-alternative therapy interactions can cause serious problems.
- C. Natural products may be more effective and the prescribed drug may not be needed.
- D. The cost of the drug and the alternative therapy may be too expensive for the patient to hand
Correct Answer: B
Rationale: Complementary therapies can interact with prescribed drugs, posing risks that the nurse must identify.