Nokea
Which of the following is NOT part of the histology of non-alcoholic steatohepatitis?
- A. Fatty infiltration in liver
- B. Fibrosis of liver
- C. Inflammatory infiltrates in lobules
- D. Cirrhosis
Correct Answer: D
Rationale: NASH histology includes steatosis (fatty infiltration), lobular inflammation, and fibrosis, per pathology definitions. Mallory bodies (intracellular inclusions) are classic but not universal. Cirrhosis is an advanced NAFLD outcome, not a defining NASH feature progression, not initial histology. This distinction aids physicians in staging chronic liver disease accurately.
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Strategies to overcome barriers and challenges faced in insulin therapy include the following EXCEPT:
- A. Close supervision for the patient's first jab
- B. Threaten patient into adherence with insulin therapy
- C. Engage patient from the start
- D. Offer the least painful options currently available in the market
Correct Answer: B
Rationale: Insulin wins guide first shots, engage early, ease pain, set sharp goals; threats flop, breed resentment. Nurses coach this chronic game, not bully.
Which condition assessed by the nurse would be an early warning sign of childhood cancer?
- A. Difficulty swallowing
- B. Frequent cough or hoarseness
- C. Change in bowel and bladder habits
- D. Swellings, lumps or masses anywhere on the body
Correct Answer: D
Rationale: Childhood cancers often present with subtle, non-specific signs, but swellings, lumps, or masses anywhere on the body are a key early warning, indicating possible tumors like leukemia (lymphadenopathy), Wilms tumor, or sarcomas. Nurses must assess these palpable abnormalities, as they prompt urgent diagnostic workup imaging or biopsy to catch cancer early when treatment is most effective. Difficulty swallowing might suggest esophageal or brain tumors but isn't a common early childhood cancer sign. Frequent cough or hoarseness could indicate adult cancers (e.g., lung) or late-stage disease, not typical pediatric onset. Bowel and bladder changes are more adult-specific (e.g., colorectal cancer) or late effects in children. Lumps' prominence in pediatric guidelines underscores their priority, aligning with nursing's role in early detection to improve survival rates in young patients.
Which statement about carcinogenesis is accurate?
- A. An initiated cell will always become clinical cancer.
- B. Cancer becomes a health problem once it is 1 cm in size.
- C. Normal hormones and proteins do not promote cancer growth.
- D. Tumor cells need to develop their own blood supply.
Correct Answer: D
Rationale: Carcinogenesis is the multi-step process by which normal cells transform into cancer cells, involving initiation, promotion, and progression. A key aspect of this process is angiogenesis, where tumor cells induce the formation of new blood vessels to supply nutrients and oxygen, enabling their growth beyond a minimal size. This is a critical step, as without a blood supply, tumors cannot sustain themselves or expand significantly. The statement that an initiated cell always becomes cancer is inaccurate because initiation alone is not sufficient; it requires promoters to progress. Similarly, the idea that cancer only becomes a problem at 1 cm oversimplifies the issue tumors can pose health risks earlier depending on location and type, though 1 cm is a detectable size. Normal hormones and proteins, like estrogen or growth factors, can indeed act as promoters in carcinogenesis, contradicting that option. Thus, the need for a tumor to develop its own blood supply is the most accurate statement, reflecting a fundamental biological requirement for cancer progression, which nurses must recognize when caring for oncology patients.
Endothelial dysfunction is one of the first steps in the development of atherosclerosis. Question: Which factor is NOT involved in endothelial dysfunction?
- A. Haemodynamic changes (e.g. hypertension)
- B. Inflammation
- C. Lipids
- D. Proteinuria
Correct Answer: D
Rationale: Endothelial flops pressure, inflammation, lipids kick it, proteinuria's kidney, not vessel start. Nurses spot this, a chronic dysfunction trio.
What is an independent risk factor for the development of type 2 diabetes mellitus?
- A. Age
- B. Waist circumference
- C. Smoking
- D. All three options above
Correct Answer: D
Rationale: Type 2 diabetes brews from age cells tire; waist fat resists insulin; smoking inflammation tweaks glucose. All hit independently, stacking odds, a chronic trio nurses flag in every patient check, not just one picking off the list.