Nokea
Which of the following proteins are encoded by herpesviruses and required for viral DNA replication
- A. viral DNA polymerase
- B. ribonucleotide reductase
- C. neuraminidase
- D. thymidine kinase
Correct Answer: A
Rationale: The correct answer is A: viral DNA polymerase. Herpesviruses require viral DNA polymerase for viral DNA replication. This enzyme is responsible for synthesizing new DNA strands using existing viral DNA as a template. Ribonucleotide reductase (B) is not directly involved in DNA replication but in the synthesis of deoxyribonucleotides. Neuraminidase (C) is an enzyme found in influenza viruses, not herpesviruses. Thymidine kinase (D) is involved in nucleotide metabolism but is not essential for viral DNA replication in herpesviruses.
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A patient with suspicion on epidemic typhus was admitted to the hospital. Some arachnids and insects have been found in his flat. Which of them may be a carrier of the pathogen of epidemic typhus?
- A. Lice
- B. Spiders
- C. Bed-bugs
- D. Cockroaches
Correct Answer: A
Rationale: The correct answer is A: Lice. Lice, specifically body lice (Pediculus humanus corporis), are known carriers of the pathogen Rickettsia prowazekii, which causes epidemic typhus. Body lice are commonly found in unsanitary conditions and can transmit the bacteria through their bites. Spiders (choice B), bed-bugs (choice C), and cockroaches (choice D) are not known vectors of epidemic typhus. Spiders are predators that do not transmit diseases to humans, while bed-bugs and cockroaches are associated with other health issues but not epidemic typhus transmission.
Widal test is used to diagnose
- A. Syphilis
- B. Typhoid fever
- C. AIDS
- D. Lyme disease
Correct Answer: B
Rationale: The Widal test is used to diagnose typhoid fever caused by the bacteria Salmonella typhi. The test detects antibodies produced in response to the bacteria. Positive results indicate a current or past infection with typhoid fever. Choice A (Syphilis) is incorrect as it is diagnosed using different tests like RPR or TPPA. Choice C (AIDS) is diagnosed with HIV tests like ELISA or Western blot. Choice D (Lyme disease) is diagnosed using tests like ELISA or Western blot specific for Borrelia burgdorferi.
A wound smear from a patient revealed Gram-positive cocci arranged in clusters. The culture was catalase-positive and coagulase-positive. What is the causative agent?
- A. Staphylococcus aureus
- B. Streptococcus pyogenes
- C. Micrococcus luteus
- D. Enterococcus faecalis
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus aureus.
1. Gram-positive cocci in clusters suggest staphylococci.
2. Catalase-positive indicates staphylococci since streptococci are catalase-negative.
3. Coagulase-positive further confirms Staphylococcus aureus, distinguishing it from other staphylococci.
Summary: B is incorrect as Streptococcus pyogenes is catalase-negative. C is incorrect as Micrococcus luteus is catalase-negative and coagulase-negative. D is incorrect as Enterococcus faecalis is catalase-negative and coagulase-negative.
What structure allows bacteria to exchange genetic material?
- A. Pili
- B. Flagella
- C. Endospores
- D. Capsules
Correct Answer: A
Rationale: The correct answer is A: Pili. Pili are hair-like appendages on the surface of bacteria that facilitate the exchange of genetic material through a process called conjugation. During conjugation, bacteria can transfer plasmids and other genetic material to neighboring bacteria through pili. This allows for the exchange of beneficial traits like antibiotic resistance.
Choice B, Flagella, are involved in bacterial movement and not in genetic material exchange. Choice C, Endospores, are protective structures formed by bacteria in response to harsh conditions, but they are not involved in genetic material exchange. Choice D, Capsules, are protective layers around bacteria that help in adherence to surfaces and evasion of the immune system, but they do not play a role in genetic material exchange.
Bacteria that have a single polar flagellum at one end are referred to as:
- A. monotrichous
- B. monotrichous
- C. amphitrichous
- D. peritrichous
Correct Answer: B
Rationale: Step-by-step rationale:
1. Monotrichous means having a single flagellum at one end.
2. The term "polar" indicates that the flagellum is located at one end of the bacterium.
3. Therefore, bacteria with a single polar flagellum are referred to as monotrichous.
4. Choice A is a typo, as it is the same as the correct answer B.
Summary:
- Choice A is a typo, as it duplicates the correct answer.
- Choice C, amphitrichous, refers to bacteria with a flagellum at each end.
- Choice D, peritrichous, describes bacteria with flagella distributed over the entire surface.