Nokea
Which of the following represents a typical match between pathogen type and Th subset response?
- A. Virus : TH1
- B. Intracellular bacteria : TH2
- C. Virus : TH17
- D. Parasitic worm : TH1
Correct Answer: A
Rationale: The correct answer is A. Virus typically triggers a Th1 response because Th1 cells are specialized in combating intracellular pathogens like viruses. Th2 response is more common for extracellular parasites, making choice B incorrect. TH17 response is usually associated with fungal infections and autoimmune diseases, making choice C incorrect. Parasitic worms usually induce a Th2 response due to their extracellular nature, making choice D incorrect.
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The patient is experiencing fibrosis and glomerulopathy a year after a kidney transplant. Which type of rejection is occurring?
- A. Acute
- B. Chronic
- C. Delayed
- D. Hyperacute
Correct Answer: B
Rationale: Chronic rejection occurs over time and involves fibrosis and structural changes in the transplanted organ.
A patient with systemic lupus erythematosus (SLE) is admitted to the hospital for evaluation and management of acute joint inflammation. Which information obtained in the admission laboratory testing concerns you most?
- A. The blood urea nitrogen (BUN) level is elevated.
- B. The C-reactive protein (CRP) level is increased.
- C. The anti-nuclear antibody (ANA) test is positive.
- D. The lupus erythematosus (LE) cell prep is positive.
Correct Answer: A
Rationale: An elevated BUN level may indicate kidney involvement which is a serious complication of SLE. The other findings are expected in SLE and do not indicate an urgent problem. CRP is a marker of inflammation and positive ANA and LE cell prep are diagnostic of SLE but do not indicate acute complications.
What is the lag phase of the primary antibody response?
- A. 1-3 days
- B. 5-10 days
- C. 10-15 days
- D. No lag phase
Correct Answer: B
Rationale: The lag phase of the primary antibody response refers to the time it takes for the immune system to generate specific antibodies after initial exposure to an antigen. The correct answer is B (5-10 days) because during this period, B cells are activated, undergo proliferation, differentiate into plasma cells, and start producing antibodies. This process takes time as the immune system needs to recognize the antigen, mount a response, and produce sufficient antibodies. Option A (1-3 days) is too short for the full activation and differentiation of B cells. Option C (10-15 days) is too long for the typical lag phase duration. Option D (No lag phase) is incorrect because there is always a lag phase before the peak antibody production in the primary immune response.
What is the medical term for an abnormal decrease in red blood cells?
- A. Leukopenia
- B. Thrombocytopenia
- C. Anemia
- D. Hemolysis
Correct Answer: C
Rationale: The correct answer is C: Anemia. Anemia is the medical term for an abnormal decrease in red blood cells. Red blood cells are responsible for carrying oxygen throughout the body, and a decrease in their numbers can lead to symptoms like fatigue, weakness, and paleness.
Rationale:
1. Leukopenia (A) refers to a decrease in white blood cells, not red blood cells.
2. Thrombocytopenia (B) is a decrease in platelets, which are involved in blood clotting, not red blood cells.
3. Hemolysis (D) is the breakdown of red blood cells, not a decrease in their numbers.
In summary, anemia is the correct answer as it specifically describes the condition of low red blood cell count, while the other choices are related to decreases in different components of blood.
Which of the following lymphoid tissues has both hematopoietic and immune functions and acts as an emergency reservoir of blood and filters the blood as well?
- A. Tonsils and adenoids
- B. Thymus gland
- C. Spleen
- D. Lymph nodes
Correct Answer: C
Rationale: The spleen has both hematopoietic and immune functions acting as a blood filter and reservoir and plays a key role in removing old or damaged red blood cells.