ATI Immune System Quizlet Related

Review ATI Immune System Quizlet related questions and content

Which of the following statement is incorrect

  • A. Antigens in tissues can reach regional LN via afferent lymphatic vessels
  • B. Migrating dendritic cells that have collected antigens in tissues enter the draining LN via HEV
  • C. During an infection fever and other inflammatory signals induce increased blood flow to draining LN and increased chances for lymphocytes to migrate from blood into LN
  • D. The thoracic duct returns most of the circulating lymphocytes back to blood
Correct Answer: B

Rationale: The correct answer is B because migrating dendritic cells do not enter the draining lymph node (LN) via high endothelial venules (HEV); instead, they enter through afferent lymphatic vessels. HEVs are specialized post-capillary venules in LN where lymphocytes enter from the bloodstream. Dendritic cells, carrying antigens from tissues, travel via afferent lymphatic vessels to reach the LN where they present antigens to lymphocytes. Option A is correct as antigens in tissues reach LN via afferent lymphatic vessels. Option C is correct as infection-induced signals can increase blood flow to LN, facilitating lymphocyte migration. Option D is incorrect because the thoracic duct returns lymph back to the bloodstream, not specifically lymphocytes.