Which of the following statements about NSAIDs is false?
- A. NSAIDs are not recommended during pregnancy
- B. NSAIDs increase renal blood flow
- C. NSAIDs reduce the therapeutic effect of SSRIs
- D. NSAIDs have a hypocoagulability effect
Correct Answer: B
Rationale: NSAIDs decrease renal blood flow by inhibiting prostaglandins, making this statement false.
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The American Heart Association and the American Dietetic Association recommend a minimum daily fiber intake of for cardiovascular health:
- A. 10 mg/day
- B. 15 mg/day
- C. 20 mg/day
- D. 25 mg/day
Correct Answer: D
Rationale: 25 g/day of fiber is recommended to reduce cardiovascular risk by lowering cholesterol and improving glucose control.
A home care nurse visits a client recently diagnosed with diabetes mellitus who is taking Humulin NPH insulin daily. The client asks the nurse how to store the unopened vials of insulin. The nurse tells the client to:
- A. Freeze the insulin.
- B. Refrigerate the insulin.
- C. Store the insulin in a dark, dry place.
- D. Keep the insulin at room temperature.
Correct Answer: B
Rationale: Insulin in unopened vials should be stored under refrigeration until needed. Vials should not be frozen. When stored unopened under refrigeration, insulin can be used up to the expiration date on the vial. Options 1, 3, and 4 are incorrect.
Which of the following is an adverse event of glucocorticoids:
- A. Osteoporosis
- B. Hypo acid gastritis
- C. Diabetes insipidus
- D. Dehidratation
Correct Answer: A
Rationale: Osteoporosis is a common adverse effect of glucocorticoids due to bone catabolism.
The patient is taking a 2-mg dose of ropinerol XR. The drug has a half-life of 12 hours. How long will it be before only 0.25 mg of this drug remains in the patient's system?
- A. 24 hours
- B. 36 hours
- C. 48 hours
- D. 60 hours
Correct Answer: B
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to half of the peak level it previously achieved. At 12 hours there will be 1 mg of the drug available to the body. At 24 hours there will be 0.5 mg, at 36 hours there will be 0.25 mg, at 48 hours there will be 0.125 mg, and at 60 hours there will be 0.0625 mg.
A nurse is caring for a client who has a new prescription for Valproic Acid. The nurse should instruct the client that while taking this medication he will need to have which of the following laboratory tests completed periodically?
- A. Thrombocyte count
- B. Hematocrit
- C. Amylase
- D. Kidney function tests
Correct Answer: A
Rationale: Valproic acid requires monitoring of platelets for bleeding risk and liver function for hepatotoxicity.