Nokea
Which of the following statements is FALSE regarding B cells?
- A. B cells that recognize high concentrations of antigen (self) in the absence of other signals undergo apoptosis in the bone marrow
- B. Bone marrow stem cells migrate to the thymus and develop into B cells
- C. B cells synthesize antibodies and put them on their cell surface
- D. B cells can undergo class switching and produce a different antibody type
Correct Answer: B
Rationale: B cells develop in the bone marrow, not the thymus. Firstly, hematopoietic stem cells in the bone marrow give rise to B cells. They undergo maturation and selection processes in the bone marrow, not in the thymus. Therefore, choice B is false. On the other hand, choices A, C, and D are correct. A is true because B cells with high affinity to self-antigens undergo apoptosis to prevent autoimmunity. C is true since B cells synthesize antibodies which can be displayed on their surface as B cell receptors. D is true because B cells can undergo class switching to produce different types of antibodies based on the immune response requirements.
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Which bacteria are commonly associated with food poisoning?
- A. Clostridium botulinum and Staphylococcus aureus
- B. Bacillus anthracis and Mycobacterium tuberculosis
- C. Treponema pallidum and Neisseria gonorrhoeae
- D. Escherichia coli and Klebsiella pneumoniae
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum and Staphylococcus aureus. Clostridium botulinum produces a potent neurotoxin causing botulism, commonly associated with improperly canned foods. Staphylococcus aureus produces toxins causing symptoms of food poisoning. Bacillus anthracis and Mycobacterium tuberculosis are not typically associated with food poisoning. Treponema pallidum and Neisseria gonorrhoeae are bacteria causing sexually transmitted infections. Escherichia coli and Klebsiella pneumoniae are not directly linked to food poisoning.
Urine examination of a patient with acute cystitis revealed leukocytes and a lot of gram-negative bacilli. Inoculation resulted in growth of colonies of mucous nature that formed green soluble pigment. What microorganism is the most probable cause of the disease?
- A. Pseudomonas aeruginosa
- B. Klebsiella pneumoniae
- C. Escherihia coli
- D. Salmonella enteritidis
Correct Answer: C
Rationale: Rationale:
1. Presence of gram-negative bacilli suggests Enterobacteriaceae family, which includes E. coli.
2. Green soluble pigment indicates pyocyanin production, characteristic of E. coli.
3. E. coli is the most common cause of acute cystitis due to its ability to colonize the urinary tract.
Summary:
A: Pseudomonas aeruginosa is not typically associated with acute cystitis and does not produce mucous colonies.
B: Klebsiella pneumoniae may cause UTIs, but does not produce green pigment and is less common than E. coli.
D: Salmonella enteritidis is associated with gastrointestinal infections, not cystitis.
Which bacteria produce exotoxins that affect the nervous system?
- A. Clostridium botulinum and Clostridium tetani
- B. Escherichia coli and Salmonella
- C. Bacillus anthracis and Listeria monocytogenes
- D. Pseudomonas aeruginosa and Staphylococcus aureus
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum and Clostridium tetani. Both bacteria produce exotoxins that affect the nervous system. Clostridium botulinum produces botulinum toxin, causing botulism, leading to muscle paralysis. Clostridium tetani produces tetanospasmin, causing tetanus, leading to muscle stiffness and spasms.
Choice B (Escherichia coli and Salmonella) are known for causing gastrointestinal infections, not specifically affecting the nervous system. Choice C (Bacillus anthracis and Listeria monocytogenes) produce toxins that primarily affect other body systems, not the nervous system. Choice D (Pseudomonas aeruginosa and Staphylococcus aureus) are associated with skin and respiratory infections, not neurological effects.
The movement of molecules through a membrane from an area of high hydrostatic pressure to an area of lower hydrostatic pressure is:
- A. filtration
- B. exocytosis
- C. simple diffusion
- D. simple diffusion
Correct Answer: D
Rationale: The correct answer is D: simple diffusion. In simple diffusion, molecules move from an area of high concentration to low concentration without the need for energy input. Hydrostatic pressure is a form of passive transport that drives molecules to equalize concentration. Filtration (A) involves the movement of solutes through a membrane under pressure. Exocytosis (B) is the process by which cells release substances outside the cell using energy. Osmosis (C) is the movement of water molecules across a selectively permeable membrane. Therefore, simple diffusion is the most appropriate choice in this scenario.
Which type of RNA carries the genetic code for protein synthesis?
- A. mRNA
- B. tRNA
- C. rRNA
- D. snRNA
Correct Answer: A
Rationale: The correct answer is A: mRNA. mRNA carries the genetic code from the DNA in the cell nucleus to the ribosomes in the cytoplasm, where protein synthesis occurs. It serves as a template for protein synthesis by specifying the order of amino acids. tRNA (choice B) brings amino acids to the ribosome during protein synthesis. rRNA (choice C) is a structural component of ribosomes. snRNA (choice D) is involved in RNA processing and splicing, not protein synthesis. Therefore, choice A is correct as it directly carries the genetic code for protein synthesis.