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Which of the following statements is true about the medical management of diabetic ketoacidosis?

  • A. Serum lactate levels are used to guide insulin administration.
  • B. Sodium bicarbonate is a first-line medication for treatment.
  • C. The degree of acidosis is assessed through continuous pulse oximetry.
  • D. Volume replacement and insulin infusion often correct the acidosis.
Correct Answer: D

Rationale: The correct answer is D. Volume replacement and insulin infusion often correct the acidosis in diabetic ketoacidosis (DKA) because volume depletion and insulin deficiency are key factors in its pathophysiology. Volume replacement helps correct dehydration and improve tissue perfusion, while insulin infusion helps lower blood glucose levels and inhibit ketone production, ultimately correcting the acidosis.

A is incorrect because serum lactate levels are not typically used to guide insulin administration in DKA. B is incorrect as sodium bicarbonate is not a first-line medication for DKA treatment as it can worsen metabolic acidosis. C is incorrect as the degree of acidosis in DKA is typically assessed through blood gas analysis, not continuous pulse oximetry.