Nokea
Which of the following viruses belong to family Arenaviridae
- A. Lassa virus
- B. Crimean-Congo hemorrhagic fever virus
- C. Rabies virus
- D. Epstein-Bar virus
Correct Answer: A
Rationale: The correct answer is A: Lassa virus. The rationale is as follows:
1. Lassa virus is a member of the Arenaviridae family, known for causing Lassa fever.
2. Arenaviridae family includes viruses with a segmented genome and are transmitted through rodents.
3. Crimean-Congo hemorrhagic fever virus (Choice B) belongs to the Bunyaviridae family, not Arenaviridae.
4. Rabies virus (Choice C) belongs to the Rhabdoviridae family, not Arenaviridae.
5. Epstein-Barr virus (Choice D) belongs to the Herpesviridae family, not Arenaviridae.
In summary, Lassa virus is the correct choice as it aligns with the characteristics of the Arenaviridae family, while the other choices belong to different virus families.
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Protein A is located in the cell wall of:
- A. Coagulase negative staphylococcus
- B. Staphylococcus aureus
- C. Micrococcus
- D. None of them
Correct Answer: B
Rationale: Protein A is a virulence factor specific to Staphylococcus aureus. This protein binds to the Fc region of immunoglobulins, inhibiting opsonization and phagocytosis. Therefore, the correct answer is B. Coagulase negative staphylococcus (choice A) does not produce Protein A. Micrococcus (choice C) is a different genus and does not possess Protein A. Choice D is incorrect because Protein A is indeed found in Staphylococcus aureus.
The relations between the macroorganism and the resident skin microflora are defined as:
- A. Commensalism
- B. Infection
- C. Parasitism
- D. No correct answer
Correct Answer: A
Rationale: The correct answer is A: Commensalism. In this relationship, the skin microflora benefits from the host without causing harm or benefitting it. This is evident in the mutualistic interaction where the microflora receive nutrients and a place to live, while the host remains unaffected. Choice B, Infection, is incorrect because it implies harm to the host. Choice C, Parasitism, is also incorrect as it involves one organism benefiting at the expense of the other. Choice D, No correct answer, is not applicable here as Commensalism accurately describes the relationship between the macroorganism and skin microflora.
A 40-year-old man developed skin redness and an swelling in the neck area, where eventually a small abscess appeared. The section the focus is dense and yellow-green colored. In the purulent masses there are white granules. Histologically there are fungal druses, plasma and xanthome cells, and macrophages detected. Specify the most correct etiological name of this pathological process?
- A. Actinomycosis
- B. Furuncle
- C. Carbuncle
- D. Syphilis
Correct Answer: A
Rationale: The correct answer is A: Actinomycosis. This is a chronic bacterial infection caused by Actinomyces species. In this case, the description of dense yellow-green colored focus, white granules in purulent masses, and presence of fungal druses, plasma cells, xanthome cells, and macrophages all match the characteristics of actinomycosis. Actinomycosis typically presents with abscess formation containing sulfur granules, which are yellowish and granular. The other choices (B: Furuncle, C: Carbuncle, D: Syphilis) do not fit the clinical and histological features described in the question, making them incorrect options.
Pili are bacterial organelles for:
- A. Chemotaxis
- B. Adhesion
- C. Take part in the process of obtaining nutrients for bacteria
- D. None of the above
Correct Answer: B
Rationale: The correct answer is B: Adhesion. Pili are bacterial appendages that help bacteria adhere to surfaces. This is important for colonization and biofilm formation. Choice A (Chemotaxis) is incorrect because chemotaxis is the movement of bacteria in response to chemical stimuli, not the function of pili. Choice C (Nutrient acquisition) is incorrect because pili are not directly involved in obtaining nutrients. Choice D (None of the above) is incorrect as pili do serve a specific purpose, which is adhesion.
Granulomas containing lymphocytes and macrophages were detected during analysis of skin biopsy material. Among macrophages there are large cells with fat inclusions, which contain microorganisms in spheric packages (Virchow's cells). The following disease is based on the described type of hypersensitivity:
- A. Leprosy
- B. Syphilis
- C. Tuberculosis
- D. Rhinoscleroma
Correct Answer: C
Rationale: The correct answer is C: Tuberculosis. Granulomas with lymphocytes and macrophages containing Virchow's cells (large cells with fat inclusions containing microorganisms) are classic findings in tuberculosis. Leprosy (A) typically presents with granulomas but with different histopathological features. Syphilis (B) does not usually form granulomas in the skin. Rhinoscleroma (D) is a chronic bacterial infection characterized by nodular lesions but does not typically involve Virchow's cells as seen in tuberculosis.