Nokea
Which phenothiazine has the least extra pyramidal effect
- A. Thioridazine
- B. Chlorpromazine
- C. Triflupromazine
- D. Fluphenazine
Correct Answer: A
Rationale: Thioridazine has fewer extrapyramidal effects.
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Which of the following is a primary benefit of the use of computerized provider order entry for patient medications?
- A. Reduces time that prescribing drugs takes
- B. Eliminates the need to chart drugs prescribed
- C. Decreases prescribing and transcription errors
- D. Helps keep the number of drugs prescribed to a minimum
Correct Answer: C
Rationale: Computerized provider order entry reduces errors in prescribing and transcription.
The nurse transcribes an order to administer Valium 10 mg IV stat. This order is correctly interpreted by the nurse to mean it should be provided how? (Select all that apply.)
- A. As needed
- B. Immediately
- C. One time only
- D. Intravenously
Correct Answer: D
Rationale: The stat order is generally used on an emergency basis. It means that the drug is to be administered as soon as possible, but only once. IV indicates the route is intravenous. A PRN order means administer if needed. The order would specify divided doses and amount per dose if indicated.
What needs to happen to the protein-drug complex for the drugs to reach the cells where the drug can act?
- A. The protein-drug complex must break itself into smaller pieces to enter the capillaries.
- B. The binding site on the protein picks up a chemical to make it soluble in the serum.
- C. The drug must break away from the protein-binding site and float freely.
- D. The drug must be dissolved in the plasma so it can enter the capillaries and then the tissues.
Correct Answer: C
Rationale: Most drugs are bound, to some extent, to proteins in the blood to be carried into circulation. The protein-drug complex is relatively large and cannot enter into capillaries and then into tissues to react. The drug must be freed from the protein's binding site at the tissues. This occurs without the introduction of another chemical or by dissolving in it plasma.
Which of the following does albumin have the strongest affinity for?
- A. Anionic drugs
- B. Hydrophilic drugs
- C. Hydrophobic drugs
- D. A and C
Correct Answer: C
Rationale: Albumin has the strongest affinity for hydrophobic drugs , which bind to its hydrophobic pockets, unlike hydrophilic drugs; anionic drugs may bind but less preferentially.
A nurse is preparing to administer a prescribed drug. Which information about the drug would be most important for the nurse to know?
- A. Normal dosage range
- B. Special precautions in administration
- C. Drug's most common adverse effects
- D. All the above
Correct Answer: D
Rationale: The nurse must have factual knowledge of each drug given, the reason for use of the drug, the drug's general action, the more common adverse reactions associated with the drug, special precautions in administration (if any), and the normal dose ranges.