NCLEX Psychosocial Questions Related

Review NCLEX Psychosocial Questions related questions and content

Which statement best describes the pathophysiology of dementia of the Alzheimer type?

  • A. There is a genetic predisposition and dysregulation of neurotransmitters.
  • B. The dementia is transient and secondary to a physical imbalance or disorder.
  • C. Hypoxia and decreased perfusion of select areas of the brain cause tissue damage.
  • D. The presence of amyloid plaques is associated with brain tissue destruction.
Correct Answer: D

Rationale: In Alzheimer's disease, the accumulation of amyloid plaques in the brain is a hallmark feature. These plaques are associated with the destruction of brain tissue, contributing to the cognitive decline seen in dementia. Genetic predisposition and dysregulation of neurotransmitters are factors linked to the development of Alzheimer's disease, but the primary pathology lies in the amyloid plaques. Transient dementia is not characteristic of Alzheimer's disease, which is a progressive neurodegenerative disorder. Hypoxia and decreased perfusion are more typical of vascular dementia, where blood flow to the brain is compromised.