Ethical Issues in Maternal Newborn Nursing Related

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Which statement regarding chromosomal abnormalities is most accurate?

  • A. Chromosomal abnormalities occur in approximately 10% of newborns.
  • B. Abnormalities of number are the leading cause of pregnancy loss.
  • C. Down syndrome is a result of an abnormal chromosomal structure.
  • D. Unbalanced translocation results in a mild abnormality that the child will outgrow.
Correct Answer: B

Rationale: Aneuploidy is an abnormality of number that is also the leading genetic cause of mental retardation. Chromosomal abnormalities occur in fewer than 1% of newborns. Down syndrome is the most common form of a trisomal abnormality, an abnormality of chromosome number (47 chromosomes). Unbalanced translocation is an abnormality of chromosomal structure that often has serious clinical effects.