All of the following statements about efficacy and potency are true EXCEPT:
- A. Efficacy is usually a more important clinical consideration than potency
- B. Efficacy is the maximum effect of a drug
- C. Potency is a comparative measure, refers to the different doses of two drugs that are needed to produce the same effect
- D. The ED50 is a measure of drug's efficacy
Correct Answer: D
Rationale: ED50 measures potency (dose for 50% effect), not efficacy (maximal effect).
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The bronchodilator of choice for patients taking propranolol is:
- A. Albuterol
- B. Pirbuterol
- C. Formoterol
- D. Ipratropium
Correct Answer: D
Rationale: Ipratropium , an anticholinergic, avoids beta-blockade interference from propranolol, unlike beta-agonists .
A nurse is teaching a client who has a new prescription for Baclofen to treat muscle spasms. Which of the following statements by the client indicates an understanding of the teaching?(Select one that does not apply.)
- A. I will stop taking this medication right away if I develop dizziness.
- B. I know the doctor will gradually increase my dose of this medication for a while.
- C. I should increase fiber to prevent constipation from this medication.
- D. I won't be able to drink alcohol while I'm taking this medication.
Correct Answer: A
Rationale: Gradual dosing , fiber for constipation , and no alcohol reflect baclofen teaching; stopping for dizziness is incorrect.
A nurse is administering a Dopamine infusion at a low dose to a client who has severe heart failure. Which of the following findings is an expected effect of this medication?
- A. Lowered heart rate
- B. Increased myocardial contractility
- C. Decreased conduction through the AV node
- D. Vasoconstriction of renal blood vessel
Correct Answer: B
Rationale: Low-dose dopamine increases contractility via beta-adrenergic effects, improving cardiac output.
Which priority action should be implemented when hives are assessed on a patient started on a new medication?
- A. Notify physician of allergic reaction
- B. Notify physician of idiosyncratic reaction
- C. Notify physician of potential teratogenicity
- D. Notify physician of potential tolerance
Correct Answer: A
Rationale: Hives indicate an allergic reaction (hypersensitivity), requiring immediate physician notification for management.
Josie is a 5-year-old patient who presents to the clinic with a 48-hour history of nausea, vomiting, and some diarrhea. She is unable to keep fluids down and her weight is 4 pounds less than her last recorded weight. Besides IV fluids, her exam warrants the use of an antinausea medication. Which of the following would be the appropriate drug to order for Josie?
- A. Prochlorperazine (Compazine)
- B. Meclizine (Antivert)
- C. Promethazine (Phenergan)
- D. Ondansetron (Zofran)
Correct Answer: D
Rationale: Ondansetron is preferred in kids for nausea/vomiting, with fewer side effects than prochlorperazine or promethazine ; meclizine is for motion sickness.