Nokea
A nurse is planning to administer subcutaneous enoxaparin 40 mg using a prefilled syringe of Enoxaparin 40 mg/0.4 mL to an adult client following hip arthroplasty. Which of the following actions should the nurse plan to take?
- A. Expel the air bubble from the prefilled syringe before injecting.
- B. Insert the needle completely into the client's tissue.
- C. Administer the injection in the client's thigh.
- D. Aspirate carefully after inserting the needle into the client's skin
Correct Answer: B
Rationale: Inserting the needle fully ensures proper subcutaneous delivery; air bubbles are not expelled in prefilled syringes.
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Beta blockers are prescribed for diabetics with caution because of their ability to produce hypoglycemia and block the common symptoms of it. Which of the following symptoms of hypoglycemia is not blocked by these drugs and so can be used to warn diabetics of possible decreased blood glucose?
- A. Dizziness
- B. Increased heart rate
- C. Nervousness and shakiness
- D. Diaphoresis
Correct Answer: D
Rationale: Diaphoresis (sweating) is not blocked by beta blockers and signals hypoglycemia.
Which online drug reference makes available to healthcare providers and the public a standard, comprehensive, up-to-date look up and downloadable resource about medicines?
- A. American Drug Index
- B. American Hospital Formulary
- C. DailyMed
- D. Drug Reference
Correct Answer: C
Rationale: DailyMed makes available to healthcare providers and the public a standard, comprehensive, up-to-date look up and downloadable resource about medicines. The American Drug Index, American Hospital Formulary, and Drug Reference are not designed for public use in this manner.
Plasma concentration of drug at time 0 is 96(g/ml). If t½ is 2 hours concentration in plasma at 10 hours will be
- A. 48
- B. 24
- C. 12
- D. 3
Correct Answer: D
Rationale: In first-order kinetics, the concentration halves every half-life (t½ = 2 hours). At 10 hours (5 half-lives), 96 → 48 → 24 → 12 → 6 → 3 µg/ml.
Because of the pattern of cholesterol synthesis, reductase inhibitors are given:
- A. In the evening in a single daily dose
- B. Twice daily in the morning and the evening
- C. With each meal and at bedtime
- D. In the morning before eating
Correct Answer: A
Rationale: Cholesterol synthesis peaks at night, so evening dosing optimizes reductase inhibitor efficacy.
Select the first choice drug for acute gout:
- A. Colchicine
- B. Indomethacin
- C. Allopurinol
- D. Dexamethasone
Correct Answer: B
Rationale: Indomethacin, an NSAID, is the first-line treatment for acute gout due to its rapid anti-inflammatory action; colchicine is an alternative, while allopurinol is for prophylaxis.