Nokea
The client has begun medication therapy with pancrelipase (Pancrease MT). The nurse evaluates that the medication is having the optimal intended benefit if which effect is observed?
- A. Weight loss
- B. Relief of heartburn
- C. Reduction of steatorrhea
- D. Absence of abdominal pain
Correct Answer: C
Rationale: Pancrelipase (Pancrease MT) is a pancreatic enzyme used in clients with pancreatitis as a digestive aid. The medication should reduce the amount of fatty stools (steatorrhea). Another intended effect could be improved nutritional status. It is not used to treat abdominal pain or heartburn. Its use could result in weight gain but should not result in weight loss if it is aiding in digestion.
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According to the 2003-2006 National Health and Nutrition Examination Survey study of dietary intake, the group at highest risk for inadequate calcium intake was:
- A. The elderly (over age 60 years)
- B. Teenage females
- C. Teenage males
- D. Preschoolers
Correct Answer: B
Rationale: Teenage females are at high risk for inadequate calcium intake due to dietary habits and growth demands.
The mean weight of 500 college students is 70 kg and the standard deviation is 3 kg. Assuming that the weight is normally distributed, determine how many students weigh less than 64 kg.
- A. 5
- B. 11
- C. 15
- D. 20
Correct Answer: B
Rationale: Z-score: (64-70)/3 = -2. P(Z < -2) = 1 - P(Z ≤ 2). Using standard tables, P(Z ≤ 2) ≈ 0.9772, so P(Z < -2) = 1 - 0.9772 = 0.0228 (document says 0.02128, likely a typo). Then, 0.0228 * 500 ≈ 11, matching the document.
What is a prodrug
- A. Drag which increases efficiency of another drug
- B. Metabolic end product
- C. Inactive drag which gets activated in the body
- D. Drag which competes with another for metabolism
Correct Answer: C
Rationale: A prodrug is inactive until metabolized into an active form in the body.
The NP orders a thyroid panel for a patient on amiodarone. The patient tells the NP that he does not have thyroid disease and wants to know why the test is ordered. Which is a correct response?
- A. Amiodarone inhibits an enzyme that is important in making thyroid hormone and can cause hypothyroidism.
- B. Amiodarone damages the thyroid gland and can result in inflammation of that gland, causing hyperthyroidism.
- C. Amiodarone is a broad-spectrum drug with many adverse effects. Many different tests need to be done before it is given.
- D. Amiodarone can cause corneal deposits in up to 25% of patients.
Correct Answer: A
Rationale: Amiodarone inhibits thyroid hormone synthesis, risking hypothyroidism.
Candesartan and irbesartan are angiotensin receptor blockers that are used to treat hypertension. The therapeutic dose range for candesartan is 4 to 32 mg, as compared to 75 to 300 mg for irbesartan. which of the following regarding this statement is correct?
- A. Candesartan is more potent than is irbesartan
- B. Candesartan and irbesartan have different efficacy
- C. Candesartan is a non competitive antagonist for irbesartan
- D. Irbesartan is a competitive antagonist for candesartan
Correct Answer: A
Rationale: Lower dose range for candesartan indicates higher potency (lower EC50) compared to irbesartan.