Which of the following is not used for hyperthyroidism:
- A. Liothironine
- B. Levothiroxine
- C. Propilthiouracil
- D. Liotrix
Correct Answer: C
Rationale: Propylthiouracil treats hyperthyroidism; the others are thyroid hormones used for hypothyroidism.
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A pharmaceutical lab states that a drug causes negative side effects in 3 of every 100 patients. To confirm this affirmation, another laboratory chooses 5 people at random who have consumed the drug. What is the average number of patients that the laboratory should expect to experience side effects if they choose 100 patients at random?
- A. 1
- B. 2
- C. 3
- D. 4
Correct Answer: C
Rationale: The expected value (mean) of a binomial distribution is n * p. Here, n=100 and p=0.03, so U = 100 * 0.03 = 3, as calculated in the document.
Henry is 82 years old and takes two aspirin every morning to treat the arthritis pain in his back. He states the aspirin helps him to 'get going' each day. Lately he has had some heartburn from the aspirin. After ruling out an acute GI bleed, what would be an appropriate course of treatment for Henry?
- A. Add an H2 blocker such as ranitidine to his therapy
- B. Discontinue the aspirin and switch him to Vicodin for the pain
- C. Decrease the aspirin dose to one tablet daily
- D. Have Henry take an antacid 15 minutes before taking the aspirin each day
Correct Answer: A
Rationale: An H2 blocker reduces aspirin-induced heartburn; stopping or antacids don't address chronic use.
What would be the best source of drug information for a nurse?
- A. Drug Facts and Comparisons
- B. A nurses drug guide
- C. A drug package insert
- D. The Physicians Drug Reference (PDR)
Correct Answer: B
Rationale: A nurses drug guide provides nursing implications and patient teaching points that are most useful to nurses in addition to need-to-know drug information in a very user friendly organizational style. Lippincotts Nursing Drug Guide (LNDG) has drug monographs organized alphabetically and includes nursing implications and patient teaching points. Numerous other drug handbooks are also on the market and readily available for nurses to use. Although other drug reference books such as Drug Facts and Comparisons, PDR, and drug package inserts can all provide essential drug information, they will not contain nursing implications and teaching points and can be more difficult to use than nurses drug guides.
Rodrigo has been prescribed procainamide after a myocardial infarction. He is monitored for dyspnea, jugular venous distention, and peripheral edema because they may indicate:
- A. Widening of the area of infarction
- B. Onset of congestive heart failure
- C. An electrolyte imbalance involving potassium
- D. Renal dysfunction
Correct Answer: B
Rationale: These symptoms suggest heart failure, a potential procainamide complication.
A patient with an edema would have an increased volume of distribution (Vd) if?
- A. The patient was taking an anionic drug
- B. The patient was taking a hydrophobic drug
- C. The patient was taking a hydrophilic drug
- D. An edema always causes an increase in Vd
Correct Answer: C
Rationale: Edema increases extracellular fluid, raising Vd for hydrophilic drugs that distribute into this compartment, not hydrophobic drugs (tissue-bound) or universally.