Nokea
Binding of drugs to albumin is irreversible.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: False; binding to albumin is reversible, allowing drugs to dissociate and become active or available for elimination.
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Several classes of drugs have interactions with cholinergic blockers. Which of the following is true about these interactions?
- A. Drugs with a narrow therapeutic range given orally may not stay in the GI tract long enough to produce an action.
- B. Additive antimuscarinic effects may occur with antihistamines.
- C. Cholinergic blockers may decrease the sedative effects of hypnotics.
- D. Cholinergic blockers are contraindicated with antipsychotics.
Correct Answer: B
Rationale: Additive antimuscarinic effects with antihistamines can enhance side effects like sedation.
The MMR vaccine is not recommended for pregnant women because:
- A. Pregnant women do not build adequate immunity to the vaccine
- B. There is a risk of the pregnant women developing measles encephalopathy
- C. There is a risk of the fetus developing congenital rubella syndrome
- D. Pregnant women can receive the MMR vaccine
Correct Answer: C
Rationale: MMR (live vaccine) risks fetal congenital rubella syndrome ; pregnancy contraindicates it, not immunity or encephalopathy .
Which of the following statements is FALSE?
- A. Selenium sulfide is used to treat seborrheic dermatitis of scalp
- B. Gamma-benzen hexachloride is effective against scabies
- C. Psoralens are used in the treatment of vitiligo
- D. Tetannic dioxide is an absorbent sunscreen
Correct Answer: D
Rationale: Titanium dioxide is a reflective, not absorbent, sunscreen.
Anticholinergic agents, such as benztropine (Cogentin), may be given with a phenothiazine to:
- A. Reduce the chance of tardive dyskinesia
- B. Potentiate the effects of the drug
- C. Reduce the tolerance that tends to occur
- D. Increase central nervous system 4 (iNS) rdey
Correct Answer: A
Rationale: Benztropine reduces EPS, which can precede tardive dyskinesia in phenothiazine use.
You are going to prescribe a drug and the electronic health record (EHR) alerts you that there is a potential drug-drug interaction. The alert is generated by:
- A. The Food and Drug Administration MedWatch system
- B. TOXNET, the National Institutes of Health alert system
- C. The EHR clinical decision support system
- D. Lexicomp, a commercial medication alert system
Correct Answer: C
Rationale: EHR clinical decision support systems generate real-time drug interaction alerts.