Nokea
Direct renin inhibitors have the following properties. They:
- A. Are primarily generic drugs
- B. Are a renin-angiotensin-aldosterone system (RAAS) medication that is safe during pregnancy
- C. Can be used with an angiotensin-converting enzyme and angiotensin II receptor blocker medications for stronger impact
- D. Shut down' the entire RAAS cycle
Correct Answer: C
Rationale: Direct renin inhibitors (e.g., aliskiren) can be combined with ACEIs or ARBs for enhanced RAAS blockade.
You may also like to solve these questions
It is often necessary to obtain baseline data prior to initiating many forms of drug therapy. These baseline data include what? (Select all that apply.)
- A. Education level
- B. Allergies
- C. wealth
- D. Number of members in family
Correct Answer: B
Rationale: Allergies and drug use directly impact therapy safety and efficacy; education and family size are less relevant.
What is the fraction of unchanged drug reaching the systemic circulation?
- A. Elimination
- B. Bioavailability
- C. Metabolism
- D. Drug displacement
Correct Answer: B
Rationale: Bioavailability is defined as the fraction of unchanged drug that reaches systemic circulation, a key pharmacokinetic parameter.
Midazolam as compared to diazepam is:
- A. Less cerebroprotective
- B. More cerebroprotective
- C. Same as diazepam
- D. No cerebroprotective effect
Correct Answer: A
Rationale: Midazolam is less cerebroprotective than diazepam.
The following drugs are excreted in the bile except:
- A. Erythromycin
- B. Novobiocin
- C. Chloramphenicol
- D. Rifampicin
Correct Answer: C
Rationale: Chloramphenicol is primarily excreted via the kidneys, not bile.
While studying for the test, the nursing student encounters the following drug: papaverine (Pavabid). What does the nursing student identify the name Pavabid as?
- A. The generic name
- B. The chemical name
- C. The brand name
- D. The chemical and generic name
Correct Answer: C
Rationale: Several clues indicate the brand name including capitalization of the first letter in the name and in parentheses. Generic names are not capitalized; chemical names are descriptions of the chemistry of the medication resulting in complicated names.