The following drugs reduce mortality in congestive cardiac failure EXCEPT:
- A. Captopril
- B. Carvedilol
- C. Digoxin
- D. Enalapril
Correct Answer: C
Rationale: Digoxin improves symptoms but does not reduce mortality in heart failure.
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Which hormones are produces by pancreas?
- A. Calcitirne
- B. Corticotropin
- C. Insuline
- D. Dopamine
Correct Answer: C
Rationale: Insulin and glucagon are produced by the pancreas, regulating blood glucose levels; the others are not pancreatic hormones.
Administration of sulfonamide may intensify the action of tolbutamide, through:
- A. Activation of the islets of pancreas
- B. Direct action on the utilization of glucose
- C. Synergistic action
- D. Competing with tolbutamide in plasma protein binding
Correct Answer: D
Rationale: Sulfonamides displace tolbutamide from plasma proteins, increasing free drug levels and enhancing its hypoglycemic effect.
A nurse in a provider's office is monitoring serum electrolytes for four older adult clients who take digoxin. Which of the following electrolyte values increases a client's risk for Digoxin toxicity?
- A. Calcium 9.2 mg/dL
- B. Calcium 10.3 mg/dL
- C. Potassium 3.4 mEq/L
- D. Potassium 4.8 mEq/
Correct Answer: C
Rationale: Hypokalemia (3.4 mEq/L, C) increases digoxin toxicity risk by enhancing its effects.
All the following statements regarding treatment of parkinson's disese are correct except
- A. Levodopa is usually administered alone (KAR93)
- B. Amantadine is effective in the treatment of early disease
- C. Bromocryptine is a useful dopamine receptor agonist
- D. Patient may require medication every 2 hours
Correct Answer: A
Rationale: Levodopa is typically combined with carbidopa, not given alone.
Direct renin inhibitors have the following properties. They:
- A. Are primarily generic drugs
- B. Are a renin-angiotensin-aldosterone system (RAAS) medication that is safe during pregnancy
- C. Can be used with an angiotensin-converting enzyme and angiotensin II receptor blocker medications for stronger impact
- D. Shut down' the entire RAAS cycle
Correct Answer: C
Rationale: Direct renin inhibitors (e.g., aliskiren) can be combined with ACEIs or ARBs for enhanced RAAS blockade.