Nokea
The elderly are at high risk of ADRs due to:
- A. Having greater muscle mass than younger adults, leading to higher volume of distribution
- B. The extensive studies that have been conducted on drug safety in this age group
- C. The blood-brain barrier being less permeable, requiring higher doses to achieve therapeutic effect
- D. Age-related decrease in renal function
Correct Answer: D
Rationale: Age-related renal decline slows drug clearance, raising ADR risk in the elderly, unlike muscle mass , studies , or BBB .
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Which of the following names may be assigned to a drug during the process of development? (Select one that does not apply.)
- A. Chemical name
- B. Official name
- C. Pharmacologic name
- D. Trade name
Correct Answer: C
Rationale: Throughout the process of development, drugs may have several names assigned to them including a chemical name, a generic (nonproprietary) name, an official name, and a trade or brand name.
Which of the following medications is classified as a Class IA antiarrhythmic?
- A. Amiodarone
- B. Quinidine
- C. Sotalol
- D. Diltiazem
Correct Answer: B
Rationale: Quinidine is a Class IA antiarrhythmic, blocking sodium channels and prolonging the action potential.
Which of the following statements about NSAIDs is false?
- A. NSAIDs are not recommended during pregnancy
- B. NSAIDs increase renal blood flow
- C. NSAIDs reduce the therapeutic effect of SSRIs
- D. NSAIDs have a hypocoagulability effect
Correct Answer: B
Rationale: NSAIDs decrease renal blood flow by inhibiting prostaglandins, making this statement false.
A nurse is preparing to administer Amoxicillin 20 mg/kg/day PO to divide equally every 12 hr to a preschooler who weighs 44 lb. The amount available is amoxicillin suspension 250 mg/5 mL. how many mL should the nurse administer per dose? (Round the answer to the nearest whole number. Do not use a trailing zero.)
- A. 4
- B. 7
- C. 1
- D. 10
Correct Answer: A
Rationale: Calculation: 44 lb = 20 kg; 20 mg/kg/day 20 kg = 400 mg/day; 400 mg ÷ 2 doses = 200 mg/dose; 200 mg ÷ (250 mg/5 mL) = 4 mL, matching the answer.
The nurse is discussing smoking cessation with a nurse colleague who smokes. Which statement indicates a readiness to quit smoking?
- A. I don't smoke around my children or inside the house
- B. I want to stop smoking, but I will need help to do it
- C. I will quit so my co-workers will stop harassing me about it
- D. If I cut down gradually, I should be able to quit
Correct Answer: B
Rationale: Readiness shows intent and help-seeking; external pressure or gradual cutdown don't confirm it. Patients exhibit readiness when they state a desire to quit along with a request for professional assistance.