Why are endothelial cells in particular sensitive to the damage caused by high plasma glucose levels?
- A. Endothelial cells have a high metabolic activity
- B. Endothelial cells cannot regulate the glucose uptake
- C. Endothelial cells have a low level of antioxidants
- D. All statements provided above are correct
Correct Answer: B
Rationale: Endothelial cells drown in glucose no uptake brakes, high sugar slams them, not just metabolism or low shields. A chronic vessel weak spot nurses watch this sugar soak.
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Which of the following is NOT an early warning symptom of hypoglycaemia?
- A. Tremors
- B. Palpitations
- C. Diaphoresis
- D. Giddiness, drowsiness
Correct Answer: D
Rationale: Hypo's early buzz tremors, palpitations, sweat, anxiety screams adrenaline, waking patients to act. Giddiness and drowsiness lag, hitting as brain sugar drops, a later neuroglycopenic fade, not the first alarm. Clinicians teach this split, pushing quick carbs at the front signs, a chronic drill to dodge the haze.
Chemotherapeutic treatment of acute leukemia is done in four phases. Place these phases in the correct order.
- A. Maintenance
- B. Induction
- C. Intensification
- D. Consolidation
Correct Answer: B
Rationale: Acute leukemia's chemotherapy unfolds systematically: induction kicks off, aggressively killing leukemia cells to induce remission, a high-dose blitz. Intensification follows, targeting residual cells over months, relentless in early remission. Consolidation reinforces, eliminating lingering blasts post-remission, solidifying gains. Maintenance, with lower doses, sustains remission long-term, preventing relapse. This order induction, intensification, consolidation, maintenance mirrors the disease's need for initial eradication then sustained control, a structured approach nurses reinforce through patient education and monitoring, ensuring each phase's purpose aligns with leukemia's aggressive biology and treatment goals.
About the mineralocorticoid antagonists (MRAs) which of the following is correct?
- A. Patiromer is a new MRA
- B. Losartan is a MRA
- C. MRAs can cause hypokalemia
- D. Finerenone is a novel nonsteroidal MRA
Correct Answer: D
Rationale: MRAs finerenone's new, not patiromer, losartan; hyperkalemia, albumin cuts fit. Nurses tap this chronic kidney tweak.
Which antibiotic is not recommended as first line therapy for the associated bug?
- A. legionella - erythromycin
- B. chlamydia psittaci - doxycycline
- C. chlamydia pneumoniae - doxycycline
- D. mycoplasma pneumoniae - roxithromycin
Correct Answer: C
Rationale: Chlamydia pneumoniae doxycycline's gold, not erythromycin, roxi, or others mispaired. Nurses tweak this chronic lung fix.
A client with a history of prostate cancer is in the clinic and reports new onset of severe low back pain. What action by the nurse is most appropriate?
- A. Assess the client's gait and balance.
- B. Ask the client about the ease of urine flow.
- C. Document the report completely.
- D. Inquire about the client's job risks.
Correct Answer: A
Rationale: Prostate cancer commonly metastasizes to bones, especially the spine, causing spinal cord compression a medical emergency that can lead to paralysis if untreated. New, severe low back pain in this context suggests possible metastasis, making gait and balance assessment the most appropriate action to check for neurological deficits (e.g., weakness, unsteady gait) indicating compression. This prioritizes client safety, as falls or worsening paralysis could result without intervention. Asking about urine flow relates to prostate obstruction, less urgent here given the pain's prominence. Documentation is essential but passive without assessment. Job risks might contribute to back pain but are secondary to cancer history. Assessing gait and balance first ensures rapid escalation if needed, reflecting oncology nursing's focus on detecting metastatic complications early.