Nokea
Ionizing radiation involves all of the following except
- A. UV light
- B. Gamma rays
- C. Electron beams
- D. X-rays
Correct Answer: A
Rationale: Ionizing radiation has enough energy to remove tightly bound electrons from atoms, creating charged particles (ions). UV light does not have enough energy to ionize atoms, making choice A the correct answer. Gamma rays, electron beams, and X-rays all have sufficient energy to cause ionization. Gamma rays are very high-energy electromagnetic radiation, electron beams are streams of high-energy electrons, and X-rays are high-energy electromagnetic radiation as well.
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After consumption some tinned meat a patient had diplopia, acute headache, deglutition disorder, hard breathing, muscle weakness. The diagnosis was botulism. What factor of pathogenicity are the clinic presentations of this disease connected with?
- A. Exotoxin B.Hemolysin C.Endotoxin D.Plasmocoagulase E.Fibrinolysin
Correct Answer: A
Rationale: The correct answer is A, Exotoxin. Botulism is caused by the exotoxin produced by Clostridium botulinum bacteria. The symptoms described - diplopia, acute headache, deglutition disorder, hard breathing, muscle weakness - are all consistent with botulism due to the neurotoxic effects of the exotoxin. The exotoxin interferes with neurotransmission at the neuromuscular junction, leading to muscle paralysis and the symptoms mentioned. The other choices (B, C, D, E) are incorrect as they do not correspond to the pathogenic mechanism of botulism and do not explain the specific clinical manifestations observed in this case.
The bacteria that produces a thick pseudomembrane in the throat is:
- A. Corynebacterium diphtheriae
- B. Streptococcus pyogenes
- C. Neisseria meningitidis
- D. Bacillus cereus
Correct Answer: A
Rationale: Rationale:
1. Corynebacterium diphtheriae is the correct answer as it is the bacteria responsible for causing diphtheria, characterized by a thick pseudomembrane in the throat.
2. Streptococcus pyogenes causes strep throat but does not produce a pseudomembrane.
3. Neisseria meningitidis causes meningitis and septicemia, not a throat pseudomembrane.
4. Bacillus cereus causes food poisoning, not throat-related symptoms.
A 32 year old patient complains about heartburn and dull pain in the epigastrium that appear 2-3 hours after meal. Exacerbations happen in spring and in autumn. The patient has food intolerance of eggs and fish. Objectively: stomach palpation reveals painfulness in the gastroduodenal area. Electrophasoduodenoscopy revealed a 5 mm ulcer on the anterior wall of duodenum. Urease test is positive. What is the most probable leading mechanism of disease development?
- A. Helicobacterial infection
- B. Dietary allergy
- C. Autoantibody production
- D. Reduced prostaglandin synthesis
Correct Answer: A
Rationale: The correct answer is A: Helicobacterial infection. This is the most probable leading mechanism of disease development in this case because the patient's symptoms, such as heartburn, epigastric pain, food intolerance, and presence of a duodenal ulcer with a positive urease test, are classic signs of Helicobacter pylori infection. This bacterium colonizes the stomach lining, leading to inflammation and ulcer formation. The exacerbations in spring and autumn could be due to seasonal variations in immune response.
Choice B: Dietary allergy is incorrect because the symptoms and findings in the patient are more indicative of an infectious etiology rather than an allergic reaction to specific foods.
Choice C: Autoantibody production is unlikely as there are no indications of an autoimmune process in this case.
Choice D: Reduced prostaglandin synthesis is not the leading mechanism as the symptoms and findings are more consistent with an infectious cause rather than a deficiency in prostaglandin synthesis.
For family Togaviridae is true that
- A. they have helical type of symmetry
- B. they have non-segmented (-)dsRNA
- C. they have non-segmented (+)ssRNA
- D. they are non-enveloped viruses
Correct Answer: C
Rationale: Step 1: Togaviridae is a family of viruses known to have non-segmented (+)ssRNA as their genetic material.
Step 2: The positive sense RNA means that the viral RNA can be directly translated into proteins by host machinery.
Step 3: This RNA genome acts as mRNA, allowing for immediate translation of viral proteins.
Step 4: Therefore, choice C is correct as it accurately describes the genetic nature of Togaviridae.
Summary:
- Choice A is incorrect because Togaviridae viruses do not have helical symmetry.
- Choice B is incorrect because Togaviridae viruses do not have non-segmented (-)dsRNA.
- Choice D is incorrect because Togaviridae viruses are enveloped viruses.
An 18-year-old patient has enlarged inguinal lymph nodes, they are painless, thickened on palpation. In the area of genital mucous membrane there is a small-sized ulcer with thickened edges and "laquer"bottom of greyish colour. What is the most probable diagnosis?
- A. Syphilis
- B. Tuberculosis
- C. Lepra
- D. Trophic ulcer
Correct Answer: A
Rationale: The correct answer is A: Syphilis. The presentation of painless inguinal lymph nodes, along with a small-sized ulcer with thickened edges and a "laquer" bottom of greyish color on the genital mucous membrane, is classic for primary syphilis. The painless nature of the lymph nodes and the specific characteristics of the ulcer are key features of syphilitic infection. Primary syphilis is caused by the bacterium Treponema pallidum and typically presents with a single, painless ulcer known as a chancre. It is important to consider syphilis in the differential diagnosis of genital ulcers.
Summary of other choices:
B: Tuberculosis - Unlikely, as tuberculosis typically presents with pulmonary symptoms and does not cause genital ulcers.
C: Lepra - Unlikely, as leprosy does not typically present with painless inguinal lymph nodes and the specific ulcer characteristics described.
D: Trophic ulcer - Unlikely