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The nurse is reinforcing teaching to a person being tested for HIV in a clinic. Which test should the nurse explain is done first in HIV testing?
- A. ELISA test
- B. Western blot test
- C. Viral load studies
- D. Rheumatoid factor test
Correct Answer: A
Rationale: The correct answer is A: ELISA test. The ELISA test is typically the initial screening test for HIV due to its high sensitivity in detecting HIV antibodies. It is cost-effective and quick. Western blot test is a confirmatory test used if ELISA is positive. Viral load studies monitor the progression of the disease but are not typically done first. Rheumatoid factor test is unrelated to HIV testing. Therefore, the ELISA test is the most appropriate initial step in HIV testing.
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Which normal tissues manifest early, acute responses to radiation therapy?
- A. Spleen and liver
- B. Kidney and nervous tissue
- C. Bone marrow and gastrointestinal (GI) mucosa
- D. Hollow organs such as the stomach and bladder
Correct Answer: C
Rationale: Bone marrow and GI mucosa are highly sensitive to radiation and show early acute responses.
What is the correct order of steps needed for 2nd generation sequencing?
- A. DNA fragmentation, DNA isolation, amplification, primer ligation, sequencing
- B. Amplification, primer ligation, sequencing, DNA fragmentation, DNA isolation
- C. DNA isolation, DNA fragmentation, primer ligation, amplification, sequencing
- D. Sequencing, DNA isolation, DNA fragmentation, primer ligation, amplification
Correct Answer: C
Rationale: The correct order of steps for 2nd generation sequencing is C: DNA isolation, DNA fragmentation, primer ligation, amplification, sequencing. Firstly, DNA isolation is crucial to extract the DNA from the sample. Next, DNA fragmentation breaks the DNA into smaller fragments for sequencing. Primer ligation involves attaching primers to the DNA fragments. Amplification is necessary to make multiple copies of the DNA fragments for sequencing. Finally, sequencing is the process of determining the nucleotide sequence of the DNA fragments. This order ensures that the DNA is properly prepared and amplified before sequencing, leading to accurate results.
Choices A, B, and D are incorrect because they do not follow the correct sequence of steps required for 2nd generation sequencing. Incorrect sequences may lead to errors in the sequencing process and inaccurate results.
What chemicals are responsible for the flavor and holes in Swiss cheese?
- A. lactate, oxygen
- B. propionic acid, carbon dioxide
- C. acetic acid, carbon dioxide
- D. ethanol, hydrogen
Correct Answer: B
Rationale: The correct answer is B: propionic acid, carbon dioxide. Propionic acid is produced by bacteria in Swiss cheese, contributing to its nutty flavor. The bacteria also produce carbon dioxide, which forms the characteristic holes. Lactate (A) is a byproduct of bacteria in cheese but not responsible for the flavor or holes. Acetic acid (C) is not commonly found in Swiss cheese. Ethanol (D) and hydrogen are not involved in the flavor or hole formation.
The major role of the complement system is to work in conjunction with
- A. antibodies to lyse cells via the C8 and C9 components
- B. the major histocompatibility complex for cell recognition
- C. antibodies to opsonize cells
- D. the T-cell receptor for production of lymphokines
Correct Answer: A
Rationale: Rationale: The complement system is a group of proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens. Choice A is correct because the C8 and C9 components of the complement system form the membrane attack complex which lyses cells. Choices B, C, and D are incorrect because the complement system primarily functions independently of the major histocompatibility complex, antibodies for opsonization, and T-cell receptor for lymphokine production.
A patient in Russell traction with a Pearson attachment for a fracture of the tibia complains of intense pain at the fracture site. The nurse assesses a temperature of 102° F and increased swelling at the fracture site. Which complication do these findings suggest?
- A. Osteomyelitis
- B. Fat embolism
- C. Traction misalignment
- D. Nonunion of the fracture
Correct Answer: A
Rationale: The correct answer is A: Osteomyelitis. The combination of intense pain, increased swelling, elevated temperature, and presence of traction indicates an infection in the bone, suggesting osteomyelitis. This serious complication requires prompt treatment with antibiotics.
Incorrect choices:
B: Fat embolism - This typically presents with respiratory distress, petechiae, and neurological changes, not with localized pain and swelling.
C: Traction misalignment - This would cause a change in the alignment of the fracture but would not typically present with fever and localized signs of infection.
D: Nonunion of the fracture - Nonunion is a failure of the bone to heal, which would not typically present with the acute signs of infection seen in this case.