The client with gastroesophageal reflux disease (GERD) is being taught about dietary modifications by the nurse. Which instruction should the nurse include?
- A. Increase your intake of spicy foods.
- B. Avoid lying down immediately after eating.
- C. Consume a high-fat diet.
- D. Drink caffeinated beverages with meals.
Correct Answer: B
Rationale: The correct answer is B: Avoid lying down immediately after eating. This instruction helps prevent acid reflux by allowing gravity to aid in digestion. Lying down can cause stomach acid to flow back up the esophagus, exacerbating GERD symptoms. Increasing intake of spicy foods (A) can irritate the esophagus, consuming a high-fat diet (C) can delay stomach emptying and worsen symptoms, and drinking caffeinated beverages with meals (D) can relax the lower esophageal sphincter, leading to more reflux.
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A 55-year-old man presents with jaundice, pruritus, and dark urine. Laboratory tests reveal elevated bilirubin and alkaline phosphatase. Imaging shows dilated intrahepatic bile ducts and a normal common bile duct. What is the most likely diagnosis?
- A. Primary biliary cirrhosis
- B. Primary sclerosing cholangitis
- C. Gallstones
- D. Pancreatic cancer
Correct Answer: A
Rationale: The most likely diagnosis is Primary biliary cirrhosis (PBC). PBC typically presents with jaundice, pruritus, and dark urine due to impaired bile flow. Elevated bilirubin and alkaline phosphatase levels are common in PBC. Imaging findings of dilated intrahepatic bile ducts and a normal common bile duct support the diagnosis of PBC. Primary sclerosing cholangitis (Choice B) would show strictures and beading of bile ducts on imaging. Gallstones (Choice C) would typically present with a common bile duct obstruction. Pancreatic cancer (Choice D) may present with similar symptoms but is less likely given the specific imaging findings in this case.
A 50-year-old man presents with fatigue, arthralgia, and darkening of the skin. Laboratory tests reveal elevated liver enzymes and high serum ferritin levels. What is the most likely diagnosis?
- A. Wilson's disease
- B. Hemochromatosis
- C. Alpha-1 antitrypsin deficiency
- D. Autoimmune hepatitis
Correct Answer: B
Rationale: The correct answer is B: Hemochromatosis. In this case, the patient's symptoms of fatigue, arthralgia, darkening of the skin, elevated liver enzymes, and high serum ferritin levels point towards iron overload disorder. Hemochromatosis is a genetic condition characterized by excessive absorption and accumulation of iron in various organs, leading to liver damage and skin pigmentation. Wilson's disease (A) presents with copper accumulation, not iron. Alpha-1 antitrypsin deficiency (C) primarily affects the lungs and liver, not causing iron overload. Autoimmune hepatitis (D) does not typically present with elevated ferritin levels.
A 35-year-old man presents with difficulty swallowing, weight loss, and regurgitation of undigested food. A barium swallow shows a 'bird beak' appearance of the lower esophagus. What is the most likely diagnosis?
- A. Esophageal cancer
- B. Achalasia
- C. Peptic stricture
- D. Gastroesophageal reflux disease
Correct Answer: B
Rationale: The correct answer is B: Achalasia. The presentation of difficulty swallowing, weight loss, regurgitation of undigested food, and 'bird beak' appearance on barium swallow are classic for achalasia. In achalasia, there is impaired relaxation of the lower esophageal sphincter and absent peristalsis in the esophagus. This leads to functional obstruction and dilation of the esophagus, causing the characteristic 'bird beak' appearance.
Incorrect Choices:
A: Esophageal cancer typically presents with progressive dysphagia, weight loss, and may show a mass or stricture on imaging.
C: Peptic stricture is usually seen in patients with long-standing gastroesophageal reflux disease or esophagitis. Symptoms are often related to acid reflux.
D: Gastroesophageal reflux disease commonly presents with heartburn, regurgitation, and chest pain. It does not typically cause weight loss or the 'bird
A 60-year-old man presents with fatigue, weight gain, and constipation. Laboratory tests reveal low TSH and high free T4 levels. What is the most likely diagnosis?
- A. Hypothyroidism
- B. Hyperthyroidism
- C. Thyroiditis
- D. Thyroid cancer
Correct Answer: B
Rationale: The correct answer is B: Hyperthyroidism. In this case, the low TSH and high free T4 levels indicate an overactive thyroid gland, leading to symptoms like fatigue, weight gain, and constipation. The low TSH is due to negative feedback as the high free T4 suppresses TSH production. Hyperthyroidism fits this clinical picture, as opposed to hypothyroidism (choice A) which would have high TSH and low free T4 levels. Thyroiditis (choice C) typically presents with symptoms of both hyperthyroidism and hypothyroidism and is usually transient. Thyroid cancer (choice D) is less likely given the presentation of symptoms and specific lab results.
Which regimen is most effective for treating H. pylori infection?
- A. Metronidazole, bismuth subsalicylate, amoxicillin for 14 days
- B. Clarithromycin and omeprazole for 14 days
- C. Metronidazole, lansoprazole, and clarithromycin for 14 days
- D. Metronidazole, clarithromycin, and omeprazole for 7 days
Correct Answer: C
Rationale: The correct answer is C - Metronidazole, lansoprazole, and clarithromycin for 14 days. This regimen includes a proton pump inhibitor (lansoprazole) to reduce stomach acid, clarithromycin to kill the bacteria, and metronidazole as an alternative antibiotic. This combination therapy is recommended by guidelines as it targets H. pylori effectively, reducing the risk of resistance.
Choice A is incorrect as bismuth subsalicylate is not included in the recommended regimen. Choice B is incorrect because omeprazole is not the preferred proton pump inhibitor, and using clarithromycin alone can lead to resistance. Choice D is incorrect as the duration of treatment is insufficient for eradication. Overall, choice C is the most effective option based on current guidelines and best practices for treating H. pylori infection.