ATI Hematologic System Quizlet

ATI Hematologic System Quizlet Related

Review ATI Hematologic System Quizlet related questions and content

A 12-year-old patient with localized osteosarcoma is being treated with cisplatin, doxorubicin, and high-dose methotrexate. The pain at his primary site rapidly resolves after initiation of chemotherapy. After tumor resection, pathology reveals the tumor was greater than 95% necrotic. You want to continue cisplatin, doxorubicin, and high-dose methotrexate. Which of the following is the best answer regarding the evaluations that should be performed to monitor for toxicity in patients receiving cisplatin, doxorubicin, and high-dose methotrexate?

  • A. Complete blood count, creatinine, liver function tests
  • B. Complete blood count, serum electrolytes (sodium, potassium, BUN, chloride), and EKG to monitor for prolonged QTc
  • C. Complete blood count, creatinine, serum magnesium, audiogram, and echocardiogram
  • D. Complete blood count, creatinine, serum magnesium, chest x-ray
Correct Answer: C

Rationale: The correct answer is C: Complete blood count, creatinine, serum magnesium, audiogram, and echocardiogram. This choice includes essential monitoring tests for potential toxicities associated with cisplatin, doxorubicin, and high-dose methotrexate. Here's the rationale:
1. Complete blood count: To monitor for hematologic toxicities such as anemia, neutropenia, and thrombocytopenia.
2. Creatinine: To assess renal function, as cisplatin can cause nephrotoxicity.
3. Serum magnesium: Methotrexate can cause hypomagnesemia, necessitating monitoring.
4. Audiogram: Doxorubicin can lead to hearing loss, thus an audiogram is needed for early detection.
5. Echocardiogram: Doxorubicin can cause cardiotoxicity, so an echocardiogram helps in monitoring cardiac function.
Each of the other choices lacks one or more essential monitoring tests

You may also like to solve these questions

Outstanding feature of ITP:

  • A. fever
  • B. gum bleeding
  • C. moderate splenomegaly
  • D. stema tenderness
Correct Answer: B

Rationale: The correct answer is B: gum bleeding. In Immune Thrombocytopenic Purpura (ITP), the hallmark feature is thrombocytopenia leading to mucocutaneous bleeding, including gum bleeding. Fever (choice A) is not a typical feature of ITP. Splenomegaly (choice C) can be present in chronic ITP but is not a defining feature. Sterna tenderness (choice D) is not specific to ITP and is not considered a characteristic feature. Thus, gum bleeding is the outstanding feature of ITP due to the primary pathophysiology of decreased platelet count leading to bleeding manifestations.

A patient reports severe abdominal cramping and diarrhea. Assessment reveals a temperature of 102°F (38.8°C) and pulse of 82 beats/min. Results of a complete blood count reveal lower than normal segmented and banded neutrophils and higher than normal lymphocytes. Which type of infection does the nurse suspect this patient is most likely experiencing?

  • A. Viral
  • B. Fungal
  • C. Parasitic
  • D. Bacterial
Correct Answer: A

Rationale: The correct answer is A: Viral. The patient's symptoms of abdominal cramping, diarrhea, fever, and altered white blood cell count with low neutrophils and high lymphocytes suggest a viral infection. Viral infections often present with these symptoms and characteristic lab findings. Other choices are incorrect because fungal infections typically do not cause acute abdominal symptoms, parasitic infections usually present with different symptoms and lab findings, and bacterial infections are more likely to have elevated neutrophils and different clinical presentation.

The patient is a 2-month-old boy who presented with a skin abscess and is febrile. On exam, he is noted to have silvery hair and hypopigmented skin. A CBC shows a leukocyte count of 3.4 K/mcL with 10% neutrophils. What does the abnormality on the peripheral smear suggest?

  • A. Abnormal lysosomal biogenesis
  • B. Abnormal ribosome function
  • C. Abnormal phagocytosis of opsonized particles
  • D. Abnormal mitochondrial activity
Correct Answer: A

Rationale: The correct answer is A: Abnormal lysosomal biogenesis. In this case, the clinical presentation of silvery hair and hypopigmented skin suggests a diagnosis of Chediak-Higashi syndrome, a rare autosomal recessive disorder affecting lysosomal function. The abnormal leukocyte count and neutrophil percentage indicate impaired immune function due to defective lysosomal biogenesis. The other choices, B: Abnormal ribosome function, C: Abnormal phagocytosis of opsonized particles, and D: Abnormal mitochondrial activity, do not align with the clinical presentation and laboratory findings of this specific case.

Which of the following is associated with normocytic normochromic anaemia?

  • A. Iron deficiency
  • B. Primaquine
  • C. Pregnancy
  • D. Sickle cell disease
Correct Answer: C

Rationale: Normocytic normochromic anemia is characterized by normal-sized red blood cells with normal hemoglobin content. Pregnancy is associated with this type of anemia due to increased blood volume and iron demands. Iron deficiency anemia (choice A) is typically microcytic hypochromic. Primaquine (choice B) is not known to cause normocytic normochromic anemia. Sickle cell disease (choice D) results in hemolytic anemia with abnormal red blood cell morphology. Thus, the correct answer is C as it aligns with the characteristics of normocytic normochromic anemia.

All produce microcytic anemia except:

  • A. sideroblastic an.
  • B. thalassemia
  • C. pernicious anemia
  • D. lead poisoning
Correct Answer: C

Rationale: The correct answer is C: pernicious anemia. Pernicious anemia is a macrocytic anemia caused by vitamin B12 deficiency, leading to large red blood cells. Sideroblastic anemia (A) is a type of microcytic anemia due to ineffective iron utilization. Thalassemia (B) causes microcytic anemia due to decreased production of hemoglobin. Lead poisoning (D) can also lead to microcytic anemia by disrupting heme synthesis. Therefore, pernicious anemia is the only choice that does not produce microcytic anemia.

Copyright © 2025 Nokea. All rights reserved.