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A 14-year-old patient was diagnosed with Hutchinson's triad: barrel-shaped incisors, parenchymatous keratitis and deafness. The revealed presentations are consistent with the following disease:
- A. Syphilis
- B. Toxoplasmosis
- C. Lepra
- D. Tuberculosis
Correct Answer: A
Rationale: The correct answer is A: Syphilis. Hutchinson's triad is a classic presentation of congenital syphilis in children. Barrel-shaped incisors, parenchymatous keratitis, and deafness are key manifestations. Barrel-shaped incisors result from mulberry molars, a type of abnormal tooth. Parenchymatous keratitis is an inflammation of the cornea, a common ocular sign in congenital syphilis. Deafness can occur due to damage to the auditory nerve caused by the infection. Choices B, C, and D are incorrect as they do not typically present with the specific triad of symptoms seen in congenital syphilis.
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The class of immunoglobulins most abundant in body is:
- A. IgG
- B. IgE
- C. IgD
- D. IgM
Correct Answer: A
Rationale: The correct answer is A: IgG. IgG is the most abundant class of immunoglobulins in the body, constituting about 75% of total immunoglobulins. IgG plays a crucial role in long-term immunity, neutralizing toxins, and enhancing phagocytosis. IgE is involved in allergic reactions, IgD is mainly found on B cells and functions as a receptor, and IgM is the first antibody produced in response to an infection but is less abundant compared to IgG. Therefore, IgG is the correct choice based on its abundance and diverse functions in the immune system.
A child with diarrhea had stool microscopy revealing cysts with four nuclei. What is the most likely causative agent?
- A. Entamoeba histolytica
- B. Giardia lamblia
- C. Balantidium coli
- D. Trichomonas hominis
Correct Answer: A
Rationale: The correct answer is A: Entamoeba histolytica. This pathogen is known to cause amoebic dysentery, characterized by diarrhea with bloody or mucoid stools. The presence of cysts with four nuclei in the stool microscopy is a characteristic feature of Entamoeba histolytica. Other choices are incorrect because Giardia lamblia typically presents with binucleate cysts, Balantidium coli is a ciliated protozoan, and Trichomonas hominis is a non-pathogenic parasite found in the human intestine.
Enriched growth media:
- A. Belong to the minimal media and inhibit the development of gram+ cocci
- B. Support the development of the target bacteria groups without suppressing the growth of other microorganisms
- C. Are intended for the cultivation of only one microbial species
- D. Support the development of target bacteria groups and suppress the development of other microorganisms
Correct Answer: B
Rationale: The correct answer is B because enriched growth media provide essential nutrients that support the growth of target bacteria groups without inhibiting the growth of other microorganisms. This allows for the selective cultivation of specific microbes while still allowing for the growth of other organisms present in the sample. Choice A is incorrect because enriched media do not belong to minimal media and do not inhibit the development of gram+ cocci. Choice C is incorrect because enriched media can support the growth of multiple microbial species. Choice D is incorrect because enriched media do not suppress the development of other microorganisms but rather provide nutrients to support their growth alongside the target bacteria groups.
A patient with a sore throat had a throat culture revealing Gram-positive cocci in chains. The bacteria were catalase-negative and beta-hemolytic. What is the most likely causative agent?
- A. Streptococcus pyogenes
- B. Streptococcus pneumoniae
- C. Enterococcus faecalis
- D. Staphylococcus aureus
Correct Answer: A
Rationale: The correct answer is A: Streptococcus pyogenes.
1. Gram-positive cocci in chains suggest streptococci.
2. Catalase-negative indicates it's not staphylococci.
3. Beta-hemolytic points towards Group A Streptococcus (S. pyogenes).
Summary:
B. Streptococcus pneumoniae is not beta-hemolytic.
C. Enterococcus faecalis is not typically chains.
D. Staphylococcus aureus is catalase-positive.
Which bacteria are most commonly associated with food poisoning?
- A. Clostridium botulinum
- B. Salmonella enterica
- C. Escherichia coli
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D: All of the above. Clostridium botulinum, Salmonella enterica, and Escherichia coli are all common bacteria associated with food poisoning. Clostridium botulinum produces a potent neurotoxin causing botulism. Salmonella enterica causes salmonellosis, a common foodborne illness. Escherichia coli can produce toxins leading to food poisoning. Therefore, since all three bacteria are known to cause food poisoning, the correct answer is D. Choices A, B, and C are incorrect because each of these bacteria individually is commonly associated with food poisoning, not just one of them.