Pediatric HESI Test Bank Related

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A 34 year old client is diagnosed with AIDS. His pharmacologic management includes zidovudine (AZT). During a home visit, the client states, "I don't understand how this medication works. Will it stop the infection?" What is the nurse's best response?

  • A. The medication helps to slow the disease process, but it won't cure or stop it totally
  • B. The medication blocks reverse transcriptase, the enzyme required fro HIV replication
  • C. Don't you know? There aren't medication to stop or cure HIV
  • D. No. it won't stop the infection. In fact, sometimes the HIV can become immune to the drug itself
Correct Answer: B

Rationale: The nurse's best response is, "The medication blocks reverse transcriptase, the enzyme required for HIV replication." This response provides the client with a clear and accurate explanation of how zidovudine (AZT) works. AZT is a nucleoside reverse transcriptase inhibitor (NRTI) that works by blocking the activity of reverse transcriptase, an enzyme needed for HIV replication. By inhibiting this enzyme, AZT helps to slow down the replication of the virus, reducing the viral load in the body and slowing the progression of the disease. It is important for the client to understand that while AZT can help manage HIV/AIDS, it is not a cure and will not completely eliminate the infection.