Medical Surgical ATI Proctored Exam Related

Review Medical Surgical ATI Proctored Exam related questions and content

A 45-year-old woman presents with fatigue, pruritus, and jaundice. Laboratory tests reveal elevated bilirubin and alkaline phosphatase levels. Imaging shows a normal common bile duct but dilated intrahepatic bile ducts. What is the most likely diagnosis?

  • A. Primary biliary cirrhosis
  • B. Primary sclerosing cholangitis
  • C. Gallstones
  • D. Pancreatic cancer
Correct Answer: A

Rationale: The most likely diagnosis for the 45-year-old woman with fatigue, pruritus, jaundice, elevated bilirubin and alkaline phosphatase levels, and dilated intrahepatic bile ducts is Primary Biliary Cirrhosis (PBC). PBC is an autoimmune liver disease that primarily affects middle-aged women, leading to bile duct destruction and liver damage. The elevated alkaline phosphatase levels and presence of pruritus are typical in PBC due to impaired bile flow. Imaging showing dilated intrahepatic bile ducts supports the diagnosis of PBC as it indicates bile duct damage.

Summary of other choices:
B: Primary sclerosing cholangitis typically presents with strictures and beading of bile ducts on imaging.
C: Gallstones would typically present with a common bile duct obstruction and not dilated intrahepatic bile ducts.
D: Pancreatic cancer would typically present with different imaging findings and symptoms such as