Nokea
A 60 year old male patient with a history of postural hypotension has just been diagnosed with benign prostatic hyperplasia. Which ONE of the following drugs is most suitable for the management of his condition?
- A. Prazosin
- B. Terazosin
- C. Doxazosin
- D. Tamsulosin
Correct Answer: D
Rationale: Tamsulosin, a selective alpha-1A blocker, minimizes postural hypotension compared to non-selective options.
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The nurse explains that what drug resource book is compiled from package inserts?
- A. Nurses Drug Guide
- B. Physicians Desk Reference (PDR)
- C. Drug Facts and Comparisons
- D. AMA Drug Evaluations
Correct Answer: B
Rationale: The PDR is a compilation of information found on package inserts. The Nurses Drug Guide uses more easily understood language and incorporates nursing considerations and patient teaching points. Drug Facts and Comparisons includes cost comparison, often not found in other drug resource guides. The AMA Drug Evaluations is far less biased than the PDR and includes drugs still in the research stage of development.
A nurse is assessing the patients home medication use. After listening to the patient list current medications, the nurse asks what priority question?
- A. Do you take any generic medications?
- B. Are any of these medications orphan drugs?
- C. Are these medications safe to take during pregnancy?
- D. Do you take any over-the-counter medications?
Correct Answer: D
Rationale: It is important for the nurse to specifically question use of over-the-counter medications because patients may not consider them important. The patient is unlikely to know the meaning of orphan drugs unless they too are health care providers. Safety during pregnancy, use of a generic medication, or classification of orphan drugs are things the patient would be unable to answer but could be found in reference books if the nurse wishes to research them.
A client asks the NP about the differences in drug effects between men and women. What is known about the differences between the pharmacokinetics of men and women?
- A. Body temperature varies between men and women.
- B. Muscle mass is greater in women.
- C. Percentage of fat differs between genders.
- D. Proven subjective factors exist between the genders.
Correct Answer: C
Rationale: Gender differences in pharmacokinetics are largely due to fat percentage , affecting drug distribution; muscle mass is greater in men (B is false), and temperature/subjective factors are less impactful.
Etidronate is prescribed for a postmenopausal woman who is at great risk for developing osteoporosis. Which of the following adverse effects to this drug is the patient most likely to experience?
- A. Tetany
- B. Cholelithiasis
- C. Esophagitis
- D. Renal damage from calcium stone formation
Correct Answer: C
Rationale: Bisphosphonates like etidronate commonly cause esophagitis if not taken properly.
Which of the following stimulated production of thyroid hormones:
- A. Thyrotropic hormone
- B. Corticosteroids
- C. Dopamine
- D. Somatostatine
Correct Answer: A
Rationale: Thyrotropic hormone (TSH) stimulates the thyroid to produce T3 and T4.