Adult Medical Surgical ATI Related

Review Adult Medical Surgical ATI related questions and content

A 70-year-old woman presents with fatigue, anorexia, and weight loss. She has noticed darkening of her skin, particularly in sun-exposed areas. Laboratory tests reveal hyponatremia, hyperkalemia, and low cortisol levels. What is the most likely diagnosis?

  • A. Cushing's syndrome
  • B. Addison's disease
  • C. Hypothyroidism
  • D. Pheochromocytoma
Correct Answer: B

Rationale: The most likely diagnosis for the 70-year-old woman is Addison's disease. The symptoms of fatigue, anorexia, weight loss, darkened skin, along with hyponatremia, hyperkalemia, and low cortisol levels indicate adrenal insufficiency. Addison's disease is characterized by inadequate production of cortisol and aldosterone by the adrenal glands. The darkening of the skin, known as hyperpigmentation, is a classic sign of Addison's due to increased ACTH levels stimulating melanin production. In contrast, Cushing's syndrome presents with weight gain, hypertension, and high cortisol levels. Hypothyroidism typically presents with weight gain, cold intolerance, and constipation. Pheochromocytoma presents with hypertension, palpitations, and headaches due to excess catecholamine production. Therefore, the correct diagnosis in this case is Addison's disease.