A charge nurse is planning a staff education session to discuss medications used during the care of a client experiencing alcohol withdrawal. Which of the following medications should the charge nurse include in the discussion?
- A. Lorazepam
- B. Prednisolone
- C. Disulfiram
- D. Naltrexone
Correct Answer: A
Rationale: Lorazepam and diazepam manage withdrawal symptoms; disulfiram and naltrexone are for maintenance.
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Reduce the likelihood of therapeutic failure with tamoxifen treatment
- A. Not provided in document
- B. Not provided in document
- C. Not provided in document
- D. Not provided in document
Correct Answer: B
Rationale: This question lacks options, but the answer key (ANS: 2) suggests the second choice. Strategies to reduce therapeutic failure include avoiding CYP2D6 inhibitors to ensure proper metabolism of tamoxifen to its active form.
Patients who are on long-term aspirin therapy should have ____ annually.
- A. Complete blood count
- B. Salicylate level
- C. Amylase
- D. Urine analysis
Correct Answer: A
Rationale: Annual CBC monitors for aspirin-related bleeding; salicylate isn't routine yearly.
A nurse is preparing to administer medications to a 4-month-old infant. Which of the following pharmacokinetic principles should the nurse consider when administering medications to this client?
- A. Infants have a more rapid gastric emptying time.
- B. Infants have normal liver function.
- C. Infants have a more rapid gastric emptying time.
- D. Infants have an increased ability to absorb topical medications.
Correct Answer: D
Rationale: Immature liver function affects metabolism, and increased topical absorption occurs due to thinner skin; rapid gastric emptying (A,C) is incorrect.
Prescribers have been shown to override a medication alert about a patient's allergies when:
- A. The history showed that the patient had tolerated the medication in the past
- B. The benefit outweighed the risk
- C. The medication was therapeutically appropriate and needed
- D. All of the above
Correct Answer: D
Rationale: Prescribers may override alerts if past tolerance, benefit-risk balance, or therapeutic need justifies it.
A patient has recently moved from Vermont to Southern Florida. The patient presents to the clinic complaining of dizzy spells and weakness. While conducting the admission assessment, the patient tells the nurse that he have been on the same antihypertensive drug for 6 years and had stable blood pressures and no adverse effects. Since his move, he has been having problems and he feels that the drug is no longer effective. The clinic nurse knows that one possible reason for the change in the effectiveness of the drug could be what?
- A. The impact of the placebo effect on the patient's response.
- B. The accumulative effect of the drug if it has been taken for many years.
- C. The impact of the warmer environment on the patient's physical status.
- D. Problems with patient compliance with the drug regimen while on vacation.
Correct Answer: C
Rationale: Antihypertensive drugs work to decrease the blood pressure. When a patient goes to a climate that is much warmer than usual, blood vessels dilate and the blood pressure falls. If a patient is taking an antihypertensive drug and moves to a warmer climate, there is a chance that the patient's blood pressure will drop too low, resulting in dizziness and feelings of weakness. Even mild dehydration could exacerbate these effects. Most antihypertensives are metabolized and excreted and do not accumulate in the body. Patients must be very compliant with their drug regimen on vacation. After several years on an antihypertensive drug, the effects of that drug are known; therefore, the placebo effect should not be an issue.
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