A child born with Trisomy 21 should be evaluated for which associated cardiac manifestation?
- A. Systemic hypertension
- B. Congenital heart defect
- C. Hyperlipidemia
- D. Cardiomyopathy
Correct Answer: B
Rationale: Children with Trisomy 21 (Down syndrome) have a high incidence of congenital heart defects, such as atrioventricular septal defects, and should be evaluated for these conditions.
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FISH is helpful in diagnosing:
- A. Prader-Willi syndrome
- B. Di George syndrome
- C. Klinefelter's syndrome
- D. Turner's syndrome
Correct Answer: B
Rationale: FISH (Fluorescence In Situ Hybridization) is particularly useful in diagnosing DiGeorge syndrome, which involves microdeletions on chromosome 22.
Renal damage is a recognised complication of infection with:
- A. Plasmodium Jalciparum
- B. Schistosoma haematobium
- C. Plasmodium malariae
- D. Leptospira icterohaemorrhagica
Correct Answer: D
Rationale: Leptospira icterohaemorrhagica can cause renal damage. Plasmodium species and Schistosoma are less commonly associated with renal complications.
Patients with a small PDA have the following criteria EXCEPT
- A. asymptomatic risk for endocarditis
- B. normal peripheral pulses
- C. normal pulmonary artery pressure
- D. normal life expectancy
Correct Answer: A
Rationale: Small PDAs typically have a low risk for endocarditis.
Causes for hypertension in childhood
- A. PDA
- B. Hemolytic uremic syndrome
- C. Guillain-Barre syndrome
- D. Lead poisoning
Correct Answer: A
Rationale: Patent ductus arteriosus (PDA) is a common cause of hypertension in childhood.
A 15-year-old female reports fainting at school in class on two occasions. The adolescent's orthostatic blood pressures are normal. The primary care pediatric nurse practitioner suspects a cardiac cause for these episodes and will order which tests before referring her to a pediatric cardiologist?
- A. 12-lead electrocardiogram
- B. Echocardiogram
- C. Tilt table testing
- D. Treadmill exercise testing
Correct Answer: A
Rationale: A 12-lead ECG is useful for initial evaluation.
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