Nokea
A client has a prescription for Acyclovir. Which of the following instructions should the nurse include?
- A. Expect to take this medication long-term.
- B. Increase fluid intake during therapy.
- C. Avoid sexual contact while on this medication.
- D. Consult your healthcare provider if you experience nausea.
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
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Hydrochlorothiazide is classified as a
- A. Anti-inflammatory
- B. Antiarrhythmic
- C. Diuretic
- D. Antifungal
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
The client is receiving oxytocin (Pitocin) for induction of labor. Which assessment finding will most likely result in the nurse stopping the infusion?
- A. Uterine contractions are continuous and sustained.
- B. The vaginal exam reveals that the client is entering transition.
- C. The client reports that the uterine contractions are strong in intensity.
- D. Uterine contractions occur every 2 to 3 minutes and last 40 to 60 seconds.
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
A healthcare professional is reviewing the laboratory results of a client who is taking Warfarin for atrial fibrillation. Which of the following findings should the professional report to the provider immediately?
- A. INR of 4.0
- B. Potassium level of 4.5 mEq/L
- C. Creatinine level of 1.0 mg/dL
- D. BUN of 18 mg/dL
Correct Answer: A
Rationale: An INR of 4.0 indicates that the client's blood is clotting too slowly, increasing the risk of bleeding. This level is above the therapeutic range for a client on Warfarin therapy. Therefore, the healthcare professional should notify the provider immediately to prevent potential bleeding complications.
A client has a new prescription for Hydrochlorothiazide. Which of the following instructions should the nurse include?
- A. Take the medication in the morning.
- B. Increase your intake of potassium-rich foods.
- C. Expect decreased urination within the first few days.
- D. Avoid foods high in potassium.
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Individuals who are slow acetylators (i.e. have a relatively low activity of hepatic N-acetyltransferase):
- A. Have a prevalence of 15-20 per cent in European caucasians
- B. Are more likely to develop thrombocytopenia, nephrotic syndrome and rash during gold treatment
- C. Are more likely to develop hepatotoxicity following halothane anaesthesia
- D. Are more likely to develop antinuclear antibodies during hydralazine therapy
Correct Answer: D
Rationale: Slow acetylators have reduced hepatic N-acetyltransferase (NAT2) activity, affecting metabolism of drugs like hydralazine, isoniazid, and procainamide. In European Caucasians, prevalence is actually 50-60%, not 15-20%, making that statement inaccurate. Gold treatment side effects like thrombocytopenia or nephrotic syndrome aren't strongly linked to acetylation status, but rather to immune responses, so that's less relevant. Halothane hepatotoxicity relates to immune-mediated reactions or metabolites, not acetylation speed. Hydralazine, metabolized by NAT2, accumulates in slow acetylators, increasing risk of drug-induced lupus with antinuclear antibodies (ANA), a well-documented association. Agranulocytosis with clozapine isn't tied to acetylation but to idiosyncratic reactions. The ANA risk with hydralazine is the most accurate, reflecting its pharmacogenetic implications, critical for personalized dosing and monitoring.