Fluid Maintenance Pediatrics Practice Questions Related

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A client has malignant lymphoma. As part of her chemotherapy, the physician prescribes chlorambucil (Leukeran), 10mg by mouth daily. When caring for the client, the nurse teaches her about adverse reactions to chlorambucil, such as alopecia. How soon after the first administration of chorambucil might this reaction occur?

  • A. Immediately
  • B. 2 to 3 weeks
  • C. 1 week
  • D. 1 month
Correct Answer: B

Rationale: Alopecia (hair loss) is a common adverse reaction to chlorambucil, which typically occurs within 2 to 3 weeks of starting treatment. This is because chemotherapy drugs like chlorambucil target rapidly dividing cells, which also includes hair follicles leading to hair loss. Patients should be informed about this potential side effect so that they can be prepared for it and explore options like wearing wigs or scarves if they wish.