You are discussing the risk of radiotherapy with the parents of a child with medulloblastoma; the mother has a concern about the late neurological complications post radiotherapy. The statement that should be included in the discussion that late neurological sequelae post radiotherapy is more severe with
- A. focal radiotherapy rather than craniospinal irradiation
- B. children with an age of less than 3 year
- C. concomitant chemo-radiotherapy
- D. low grade tumors rather than high grade tumors
Correct Answer: B
Rationale: Younger children (<3 years) are more susceptible to long-term neurotoxic effects of radiotherapy.
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The nurse understands that an anaphylactic reaction is considered which of the following types of hypersensitivity reactions?
- A. Type I
- B. Type III
- C. Type II
- D. Type IV
Correct Answer: A
Rationale: An anaphylactic reaction is considered a Type I hypersensitivity reaction. In Type I hypersensitivity, the immune system produces IgE antibodies in response to an allergen, leading to the release of various inflammatory mediators like histamine. This immediate systemic reaction can cause symptoms such as hives, itching, swelling, difficulty breathing, and in severe cases, anaphylactic shock. These reactions occur quickly, typically within minutes to hours after exposure to the allergen. Anaphylaxis is a medical emergency that warrants immediate intervention with epinephrine and supportive care.
gauge needle for drawing up medication and injecting it
- A. Inject the medication in the upper arm muscle
- B. Use a 1 inch needle to administer the medication
- C. Use the Z track technique to administer the medication
Correct Answer: B
Rationale: Using a 1 inch needle is the appropriate gauge needle for drawing up medication and injecting it. The length of the needle is important to ensure that the medication reaches the intended target area and is administered effectively. Shorter needles may not penetrate deep enough, while longer needles may increase the risk of complications such as injecting the medication into the wrong tissue or causing discomfort to the patient. Therefore, using a 1 inch needle is the correct choice for administering medication safely and accurately.
Which is the most common cause of anemia in preterm newborns?
- A. Frequent blood sampling
- B. Respiratory distress syndrome
- C. Meconium aspiration syndrome
- D. Persistent pulmonary hypertension
Correct Answer: A
Rationale: The most common cause of anemia in preterm newborns is frequent blood sampling. Preterm infants are often subject to numerous blood tests for various reasons such as monitoring oxygen and blood gas levels, assessing bilirubin levels, infection screening, and more. These repeated blood withdrawals lead to a loss of red blood cells and can contribute to the development of anemia in preterm infants. Anemia in preterm newborns can have significant consequences, including impaired growth and development, delayed hospital discharge, and the potential need for blood transfusions. Therefore, minimizing unnecessary blood sampling and utilizing non-invasive monitoring methods whenever possible are key strategies in preventing and managing anemia in preterm newborns.
Alveolar type of rhabdomyosarcoma accounts for approximately 1/3 of all cases of pediatric RMS and carries the poorest prognosis. Of the following, the MOST common site of involvement by alveolar type RMS is
- A. orbit
- B. middle ear
- C. extremities
- D. bladder
Correct Answer: C
Rationale: Extremities are the most common site for alveolar rhabdomyosarcoma.
The activation of B cells in humoral immunity is assisted by which of the following?
- A. Cytotoxic T cells
- B. Suppressor T cells
- C. Helper T cells
- D. Neutrophils
Correct Answer: C
Rationale: In humoral immunity, the activation of B cells is facilitated by helper T cells. Helper T cells play a crucial role in coordinating the immune response by interacting with B cells. They secrete cytokines that stimulate B cells to proliferate and differentiate into antibody-secreting plasma cells. Without the assistance of helper T cells, the activation of B cells and the production of antibodies would be impaired. Cytotoxic T cells are involved in cell-mediated immunity, supressor T cells regulate immune response, and neutrophils are involved in phagocytosis and innate immunity, but they do not directly assist in B cell activation in humoral immunity.