Pediatric Emergency Nursing PICO Questions Related

Review Pediatric Emergency Nursing PICO Questions related questions and content

. A client is prescribed prednisone (Deltasone) daily. Which statement best explains why the nurse should instruct the client to take this drug in the morning?

  • A. Taking the drug at the same time every day establishes a regular routine, reducing the risk of forgetting a dose.
  • B. Prednisone has a longer half-life with morning administration, making it more effective.
  • C. Morning administration of prednisone mimics the body's natural corticosteroid secretion pattern.
  • D. Prednisone is best absorbed when taken on an empty stomach first thing in the morning.
Correct Answer: C

Rationale: The best statement explaining why the nurse should instruct the client to take prednisone (Deltasone) in the morning is that morning administration mimics the body's natural corticosteroid secretion pattern. Cortisol, a natural corticosteroid, is highest in the morning and decreases throughout the day. By taking prednisone in the morning, the client aligns the medication's peak effects with the body's natural cortisol levels, which can help reduce the risk of disrupting the body's internal rhythm and minimize potential side effects. This timing also helps achieve optimal therapeutic effects while minimizing the risk of adrenal suppression and other adverse effects associated with corticosteroid use.